DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33331 and Tamm41

DIOPT Version :9

Sequence 1:	NP_996213.1	Gene:	CG33331 / 2768668	FlyBaseID:	FBgn0067628	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	XP_038963787.1	Gene:	Tamm41 / 362419	RGDID:	1586150	Length:	346	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	131/321 - (40%)
Similarity:	177/321 - (55%)	Gaps:	25/321 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RRTVARFPLGSVSYMFAYGSGVKQQEGYGKVGNGNNLRPPPGTVVDLVFCVRDARGFHAENLHRH 70
            ||.:|.|| ..:|..|||||.|.:|.|    .:.:...|    ::||||.|.|...:||.||.::
  Rat    14 RRILAHFP-EDLSLAFAYGSAVYRQAG----PSAHQENP----MLDLVFTVDDPVAWHAMNLKKN 69

  Fly    71 PDHYSALRHLGPNFVAKYQERLGAGVYCNTLVPLPDVGITIKYGVVSQEELLEDLLDWRHLYLAG 135
            ..|||.|:.|||..::..|...|||||.|.|:...  |..|||||:|...|:||||:|.:||:||
  Rat    70 WSHYSLLKLLGPRIISSVQNNYGAGVYFNPLIMCD--GKLIKYGVISTGTLIEDLLNWNNLYIAG 132

  Fly   136 RLHKPVTNLVNPSDNPPLKAALERNLVSALQVALLLLPEKFTAYGLFHTIAGLSYKGDFRMIFGE 200
            ||.||| .:|:.:::..|:|||::||.||:..|.|:|||.|:...||..||||||.|||||:.||
  Rat   133 RLQKPV-KIVSMNESTVLRAALDKNLKSAVTTACLMLPESFSEEDLFIEIAGLSYSGDFRMVIGE 196

  Fly   201 NKQKVHNIVSPQINDFFALYQPSLGQLSDYVAVNMKGQEPGSRKPAIIFEQDKSSSATCQHLRQL 265
            .|.||.|||.|.:..|..||:..|.:....|....:||          .|.|||.......|..|
  Rat   197 EKAKVLNIVKPNVVHFRELYESILQKDPQMVYKMHQGQ----------LEIDKSPEGQFTQLMTL 251

  Fly   266 PRELQKRLQRNAACRGDYTQVVNHLSMASQLP---EVLQASVNDIVWRSSVTQSIKNIPSA 323
            ||.||:.:.......|....|...|...:|.|   :|::.:|:.||..||:.||.|.:.:|
  Rat   252 PRTLQQHINHIMDPPGRNRDVEETLLQVAQDPDCGDVVRLAVSSIVRPSSIRQSTKGLFTA 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33331	NP_996213.1	Mmp37	5..338	CDD:286252	131/321 (41%)
Tamm41	XP_038963787.1	Mmp37	13..312	CDD:401180	130/319 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354322
Domainoid	1	1.000	208	1.000	Domainoid score	I2767
eggNOG	1	0.900	-	-		E1_KOG2986
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13754
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3615
OMA	1	1.010	-	-		QHG57884
OrthoDB	1	1.010	-	-		D1145430at2759
OrthoFinder	1	1.000	-	-		FOG0005617
OrthoInspector	1	1.000	-	-		oto98546
orthoMCL	1	0.900	-	-		OOG6_103248
Panther	1	1.100	-	-	LDO	PTHR13619
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4021
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770