DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and CG18754

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	72/284 - (25%)
Similarity:	110/284 - (38%)	Gaps:	81/284 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 GSTTP-FIVRGNEFPR-GQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCV--HRMTEDRV 331
            |.||| |..||.|... .:|||:.        .|.::.|.|||  ..|::|||||  ..:|::.:
  Fly    98 GQTTPVFRDRGAENAELNEYPWMV--------LLLYENRLSLI--RYVLTAAHCVIGGYLTQNDL 152

  Fly   332 V---VGLGRYDLD----------------------DYGEDGAEMRNVMRLLWHPDYNTRSYSDAD 371
            |   |.||....|                      .:...|...||                  |
  Fly   153 VLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRN------------------D 199

  Fly   372 IALITIERPVTFNDIIAPICMWTVEASRTVSTTGF-IAGWGRDEDSSRTQYPRVVEAEIASPTVC 435
            |||:.::.||.:...|.|||:  ::|...:..... |:||...: ||:|.....|:..  :|..|
  Fly   200 IALLRLQFPVRYTKKIQPICL--LDAEFPLQDLNLQISGWDPTK-SSQTLITSTVKER--NPADC 259

  Fly   436 ASTWRGTMVTERSLCAGNRDGSGPCVGDSGG---GLMVKQGDRWL-LRGIVSAGER-----GPAG 491
            .:.: .:..:...:|||.:.....|.|.||.   |:|....|.:: |.||.|.|::     |..|
  Fly   260 LNRY-PSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPG 323

  Fly   492 TCQLNQYVLYCDLSKHINWISENI 515
                    :|..:.....||..|:
  Fly   324 --------VYTKIGHFSEWIKANL 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	66/274 (24%)
		Tryp_SPc	277..511	CDD:214473	64/271 (24%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	65/271 (24%)
		Tryp_SPc	108..335	CDD:214473	63/268 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437206
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930