DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and CG11843

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001287578.1	Gene:	CG11843 / 43432	FlyBaseID:	FBgn0039630	Length:	316	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	82/293 - (27%)
Similarity:	119/293 - (40%)	Gaps:	63/293 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 PRSQISSVVCGREGSTTPFIVRGN-----EFPR----GQYPWLSAVYHKEVRALAFKCRGSLISS 313
            |.:.|.|.:.....|.||.||.|:     |||.    |:.|..|:      ||..| |.|.|||.
  Fly    49 PGASIESRIIDNCRSYTPLIVGGHPAQPREFPHMARLGRRPDPSS------RADWF-CGGVLISE 106

  Fly   314 SIVISAAHCVHRMTEDRVVVGLGRYDLDDYGEDGAEMRNVM--RLLWHPDYNTRSYSDADIALIT 376
            ..|::||||:.....:..||.||..|.|...||.|. |:.|  ..:.||.|....:.. ||.|:.
  Fly   107 RFVLTAAHCLESERGEVNVVRLGELDFDSLDEDAAP-RDYMVAGYIAHPGYEDPQFYH-DIGLVK 169

  Fly   377 IERPVTFNDIIAPICMWTVEASRTVSTTGFIA-GWGRDEDSSRTQYPRV----VEAEIASPTVCA 436
            :...|.|:....|.|: ..:..|  |:..||| |||   .:.....|..    |:.:.....||.
  Fly   170 LTEAVVFDLYKHPACL-PFQDER--SSDSFIAVGWG---STGLALKPSAQLLKVKLQRYGNWVCK 228

  Fly   437 STWRGTMVTER------------SLCAGNRDGSGPCVGDSGGGLMVKQGD---RWLLRGIVSA-- 484
            .     ::|.:            .||.|:......|.|||||.|::...:   .:::.||.||
  Fly   229 K-----LLTRQVEEFPRGFDGNNQLCVGSEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAGL 288

  Fly   485 --GERGPAGTCQLNQYVLYCDLSKHINWISENI 515
              |..|..|        :|..:..::.||:..:
  Fly   289 SCGSPGIPG--------IYTRVYPYLGWIARTL 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	76/271 (28%)
		Tryp_SPc	277..511	CDD:214473	74/268 (28%)
CG11843	NP_001287578.1	Tryp_SPc	68..312	CDD:238113	76/271 (28%)
CG11843	NP_001287578.1	Tryp_SPc	68..309	CDD:214473	74/268 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437655
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930