DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and CG31219

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001097837.1	Gene:	CG31219 / 42344	FlyBaseID:	FBgn0051219	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	86/301 - (28%)
Similarity:	136/301 - (45%)	Gaps:	59/301 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 PPPQRFDPRSQISSVVCGREGSTTPFIVRGNEFPRGQYPWLSAVYHKEVRALAFK--CRGSLISS 313
            |||....|    |:.:||:..||.. :|.|:|.....|||::.:.:.....|...  |.||||::
  Fly    68 PPPGNRLP----STEICGQSLSTYR-MVGGSEARPNGYPWMAMLLYLNTTTLEILPFCAGSLINN 127

  Fly   314 SIVISAAHCVHRMTEDRVV--VGLGRYDL---DDYGEDGAEMRN----------VMRLLWHPDYN 363
            ..|:::||||:.:..|..:  |.||.:|:   ..|..|..:..|          :.:::.|..::
  Fly   128 RYVLTSAHCVNGIPRDLSLKSVRLGEHDITYDPAYNPDCRDQDNQCALPNLEIKLEKIIVHGLFS 192

  Fly   364 TRSYS--DADIALITIERPVTFNDIIAPICMWTVEASRTVSTTGF-------IAGWGRDEDSSRT 419
            :.|..  :.||||:.::.||.:...|.|||         :...||       |||||:..:.
  Fly   193 SISNRNIEYDIALLRLKMPVRYRTGIMPIC---------IPKHGFFAKSKLEIAGWGKTNEG--- 245

  Fly   420 QYPRVV------EAEIASPTVCASTWRGTMVTER-SLCAGNRDGSGPCVGDSGGGLMVKQGDRWL 477
            |:.:|:      |..||   |||..:....:.:. .:|||..||...|.|||||.|||...:..:
  Fly   246 QFSQVLMHGFIRERSIA---VCALRFPYLDLNQSLQICAGGYDGVDTCQGDSGGPLMVTMDNSSV 307

  Fly   478 -LRGIVSAGERGPAGTC-QLNQYVLYCDLSKHINWISENIR 516
             |.||.:.|.:    .| |:....:|...|..:.||...:|
  Fly   308 YLAGITTYGSK----NCGQIGIPGIYTRTSAFLPWIKAVLR 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	76/271 (28%)
		Tryp_SPc	277..511	CDD:214473	74/268 (28%)
CG31219	NP_001097837.1	Tryp_SPc	88..339	CDD:214473	74/270 (27%)
CG31219	NP_001097837.1	Tryp_SPc	90..342	CDD:238113	76/270 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930