DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and CG8870

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_731802.1	Gene:	CG8870 / 41645	FlyBaseID:	FBgn0038144	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	78/285 - (27%)
Similarity:	115/285 - (40%)	Gaps:	54/285 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 CG--REGSTTPFIVRGNEFPRGQYPWLSAVYHKE----VRALAFKCRGSLISSSIVISAAHCVH- 324
            ||  |...|...|...|||     ||::.:.:..    .:.|..||.||||::..|::|||||.
  Fly    77 CGQSRRKPTKGKIPALNEF-----PWMAMLLYGNKNNLSQKLVPKCGGSLINNWYVLTAAHCVEY 136

  Fly   325 ------------RMTE-------DRVVVGLGRYDLDDYGEDGAEMRNVMRLLWHPDYNTRSYSDA 370
                        |:.|       ||.:|...|.....|.|     ..|.:::.|..:|.......
  Fly   137 PFMDYPYALKTVRLGEHNTSTNPDRAIVNGRRQYAPLYME-----IEVDQIITHEQFNRGRRLIN 196

  Fly   371 DIALITIERPVTFNDIIAPICMWTVEASRTVSTTGFIAGW---GRDEDSSRTQYPRVVEAEIASP 432
            ||||:.::.||.:...|.|||:...:...........:||   |:...|.......:.|..   |
  Fly   197 DIALVRLKFPVRYTRAIQPICLPRAQKLAAHKRKFQASGWPDMGQGIASEVLLRSFIAERH---P 258

  Fly   433 TVCASTWRGTMVTERSLCAGNRDGSGPCVGDSGGGLM--VKQGDRWL--LRGIVSAGERGPAGTC 493
            .||.|.:...:.::  :|||..||:....|||||.||  |.:|...|  ..||:|.|::    .|
  Fly   259 DVCKSNYDFNLGSQ--ICAGGLDGNDTSPGDSGGPLMETVIRGKVTLTYAAGIISYGQK----PC 317

  Fly   494 QLN--QYVLYCDLSKHINWISENIR 516
            .|.  :...|...|....||...::
  Fly   318 VLKTCKPAFYTKTSYFFEWIKSKLQ 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	74/269 (28%)
		Tryp_SPc	277..511	CDD:214473	72/266 (27%)
CG8870	NP_731802.1	Tryp_SPc	93..340	CDD:238113	73/265 (28%)
CG8870	NP_731802.1	Tryp_SPc	93..337	CDD:214473	71/262 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437236
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930