DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and CG13318

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_649831.1	Gene:	CG13318 / 41048	FlyBaseID:	FBgn0037627	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	89/354 - (25%)
Similarity:	147/354 - (41%)	Gaps:	65/354 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 PVPSVPITFAPPVPTITS---SPAPAPPP---PPPLPTPPA---------VV------TVPPATP 251
            |....|.|: ||||:|.|   |.....||   ..||||.|:         :|      |||..:.
  Fly    69 PPQVAPGTW-PPVPSIVSPGTSYCQCVPPGSCANPLPTAPSDGSGQIDIRIVNNGGYPTVPTTSS 132

  Fly   252 P---PQRFDPRSQISSVVCGRE-----GSTTPFIVRGNEFPRGQYPWLSAVYHKEVRALAFKCRG 308
            .   ........|..|..|||.     ||||   ....:...|.|||.:|:.   ..|..:...|
  Fly   133 TLTCSYGLVACCQAGSYQCGRRFPPPPGSTT---AAPGQASFGAYPWQAALL---TTADVYLGGG 191

  Fly   309 SLISSSIVISAAHCVHRMTEDRVVVGLGRYDLDDYGED-GAEMRNVMRLLWHPDYNTRSYSDADI 372
            :||::..|::|||.|:.:......|.||.:|.....|. .|:...:..:..:|.:|..:..: |:
  Fly   192 ALITAQHVLTAAHKVYNLGLTYFKVRLGEWDAASTSEPIPAQDVYISNVYVNPSFNPNNLQN-DV 255

  Fly   373 ALITIERPV--TFNDIIAPICMWTVEASRTVSTTG---FIAGWGRDEDSSRTQYPRVVEAEIASP 432
            |::.:..||  |....:..:|:      .|.|..|   ::||||:::..:...| :.:|.::..|
  Fly   256 AILKLSTPVSLTSKSTVGTVCL------PTTSFVGQRCWVAGWGKNDFGATGAY-QAIERQVDVP 313

  Fly   433 TV----CASTWRGT------MVTERS-LCAGNRDGSGPCVGDSGGGLMVKQGDRWLLRGIVSAGE 486
            .:    |.:..:.|      :::..| :|||...|...|.||.|..|:......|.:.|:|:.|
  Fly   314 LIPNANCQAALQATRLGSSFVLSPTSFICAGGEAGKDACTGDGGSPLVCTSNGVWYVVGLVAWG- 377

  Fly   487 RGPAGTCQLNQYVLYCDLSKHINWISENI 515
               .|..|.....:|.::..::.||...:
  Fly   378 ---IGCAQAGVPGVYVNVGTYLPWIQTTL 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	59/253 (23%)
		Tryp_SPc	277..511	CDD:214473	57/250 (23%)
CG13318	NP_649831.1	Tryp_SPc	169..402	CDD:238113	59/247 (24%)
CG13318	NP_649831.1	Tryp_SPc	169..399	CDD:214473	57/244 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930