DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and CG14642

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	107/397 - (26%)
Similarity:	157/397 - (39%)	Gaps:	103/397 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 GFTQPWTTVSNRSPA---VVTP----AP-TPTEIFW---------NQPVPSVPITFAPPVPTITS 225
            |..:|....|.|||.   :|.|    .| .|.|..|         ....|:.|
  Fly    30 GRMRPLQDDSIRSPVDRDIVFPELDAGPGKPEEKMWFHITDFQFDRVEGPTQP------------ 82

  Fly   226 SPAPAPPPPPPLPTPPAVVTVPPATPPPQRFDPRSQISSVVCGREGSTTPFIVR----------- 279
            .|.|...||||:|.       .|..|||..|..:......:|  |...:.::.|
  Fly    83 KPKPRQYPPPPMPG-------QPFPPPPGGFKKKENKQRRLC--EQKYSEYVERIFPNDTAVAAD 138

  Fly   280 -------GNEFPR-GQYPWLSAV-YHKEVRALAFKCRGSLISSSIVISAAHC--VHRMTEDRVVV 333
                   |....| |:||.::|| :..:...:.:||.|||||...|::||||  ::......|.:
  Fly   139 ANDADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRI 203

  Fly   334 GLGRYDLDDYGED---GAEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIAPICMWTV 395
            |    |||...|.   .|::..:.::..||:|..:.|.| ||||:.:|:.|...:.:.|:.:|..
  Fly   204 G----DLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYD-DIALLKLEKEVELTEYVRPVRLWVF 263

  Fly   396 EASRTVSTTGFIAGWG----------RDEDSSRTQYPRVVEAEIASPTVCASTWRGTMVTERSLC 450
            ....|  |..|..|:|          |..:.:.|..|. .|.....|.: |.|..|  |.|..:|
  Fly   264 PELPT--TIAFAMGYGATSFAKPMTNRLTNLNLTVVPN-AECNAELPPL-AETPSG--VLESQIC 322

  Fly   451 AG----NRDGSGPCVGDSGGGLMV-----KQGDR--WLLRGIVSAGERGPAGTCQLNQYVLYCDL 504
            |.    |||   .|.|||||.|.:     ::|.|  :.|.||.|.|.     .|:.:...:|..:
  Fly   323 AQDYILNRD---TCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGV-----FCRSSYPSVYTRV 379

  Fly   505 SKHINWI 511
            |..::||
  Fly   380 SSFLDWI 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	79/281 (28%)
		Tryp_SPc	277..511	CDD:214473	77/279 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	78/260 (30%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	76/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010