DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and CG4914

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_648711.1	Gene:	CG4914 / 39597	FlyBaseID:	FBgn0036436	Length:	374	Species:	Drosophila melanogaster

Alignment Length:	361	Identity:	98/361 - (27%)
Similarity:	144/361 - (39%)	Gaps:	83/361 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 TITSSPAPAPPPPPPLPTPPAVVT-------VP--------------------------PATPPP 253
            |..:|..||.|..|....|||..|       :|                          .|..|.
  Fly    22 TAATSATPATPATPATSAPPATSTATSSLSSIPGKYQALGAAHHQAKKLKIGDVNASSSDANKPV 86

  Fly   254 QRFDP----------------RSQIS---SVVCGREGSTTPFIVRGNEFPRGQYPWLSAVYHKEV 299
            .|.:|                ::|.|   |..|| |.:....||.|......:|||::.:.:..
  Fly    87 FRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCRCG-ERNDESRIVGGTTTGVSEYPWMARLSYFN- 149

  Fly   300 RALAFKCRGSLISSSIVISAAHCVHRMTEDRVVVGLGRYD-LDDYGEDGAEMRNVMRLLWHPDYN 363
               .|.|.|:||:...|::|||||.......:.|..|.:| .:|  ::..|.|.|:|..
  Fly   150 ---RFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRCND--KERPETRFVLRAF------ 203

  Fly   364 TRSYS----DADIALITIERPVTFNDIIAPICMWTVEASRT--VSTTGFIAGWGR-DEDSSRTQY 421
            ::.:|    |.||||:.:...|.....|.|||:..||..:.  |.|.....|||. .||...:..
  Fly   204 SQKFSFSNFDNDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSCL 268

  Fly   422 PRVVEAEIASPTVCASTWRGT--MVTERSLCAG--NRDGSGPCVGDSGGGLMVKQGD--RWLLRG 480
            .:.||..:.....|.:....|  |:|:..:|:|  ...|...|.|||||.|:..:.|  |:...|
  Fly   269 LQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIG 333

  Fly   481 IVSAGERGPAGTCQLNQYVLYCDLSKHINWISENIR 516
            |||.|.    |..:.|...:|..::|:::||.||.|
  Fly   334 IVSWGN----GCARPNYPGVYTRVTKYLDWIVENSR 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	74/250 (30%)
		Tryp_SPc	277..511	CDD:214473	72/247 (29%)
CG4914	NP_648711.1	Tryp_SPc	127..360	CDD:214473	72/248 (29%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	74/250 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910