DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and CG3700

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	90/345 - (26%)
Similarity:	143/345 - (41%)	Gaps:	47/345 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 VTPAPTPTEIFWNQPVPSVPITFAPPVPTITSSPAPAPPPPPPLPTPPAVVTVPPATPPPQRFDP 258
            :||:..|. ||:||.:....:.:......|...|.|....    ...||..|.|......|..:.
  Fly    33 LTPSDCPV-IFYNQHLIGAEVKYCDEFNDIVCCPIPLDHQ----NLKPAEQTRPFEKQCKQYNEV 92

  Fly   259 RSQISSVVCGREGSTTPFIVRGNEFPRGQYPWLSAV----YHKEVRALAFKCRGSLISSSIVISA 319
            ||...|         |||||.|.:....::|:::.:    .:|....:.:.|.||::....|::|
  Fly    93 RSACQS---------TPFIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTA 148

  Fly   320 AHCVH-----------RMTEDRVVVGLGRYDLDDYGEDG-AEMRNVMRLLWHPDYNTRSYSDA-- 370
            |||:.           .....:.||.||..|.:...:|. .:...|:..:.||.|:|......
  Fly   149 AHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFK 213

  Fly   371 -DIALITIERPVTFNDIIAPICMWTVEASRTVSTTGFIAGWGRDEDSSRTQYPRVVEAEIASPTV 434
             ||||:.::|...|||.:|.:|:.....:.....|.  ||||...|..::.:...|..:..|..|
  Fly   214 NDIALVELDRKAEFNDHVAAVCLPPDSGNDVQQVTA--AGWGFTADGVKSSHLLKVNLQRFSDEV 276

  Fly   435 CASTWRGTMVTERSLCAGNRDG-SGPCVGDSGGGLMVKQGDRWLLR---GIVS----AGERG-PA 490
            |....|.::.|....|||:... :..|.|||||.:.|:......|:   ||||    .|.:| |:
  Fly   277 CQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPS 341

  Fly   491 GTCQLNQYVLYCDLSKHINW 510
            ...:::   ||.|..:.|.|
  Fly   342 VYTKVH---LYTDWIESIVW 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	69/262 (26%)
		Tryp_SPc	277..511	CDD:214473	69/262 (26%)
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	67/258 (26%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	67/255 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100