DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and Hayan

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001097020.1	Gene:	Hayan / 32831	FlyBaseID:	FBgn0030925	Length:	637	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	109/438 - (24%)
Similarity:	178/438 - (40%)	Gaps:	103/438 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 RPPNSFFNRFYELDISGSLASFPSSVFNPFTRDGLDVNVQTVFYPTSSR----GNDIWRGFTQPW 183
            ||.||.||.                  ||      ..|...:.:..:.|    |..|......|.
  Fly   244 RPNNSNFNT------------------NP------SPNNNNLIHLVNDRLREQGMQIEPAREVPM 284

  Fly   184 TTVSNRSPAVVTPAPTPTEIF----------------------WNQPVPSVPITFAPPVPTITSS 226
            ...:..:|   |||||||::.                      ||....::.   |.|.|:|.:.
  Fly   285 VLQTTPTP---TPAPTPTQLIDPFEPYRFRGQDRDKDTQPQEPWNDVSNNLD---ADPAPSIFNP 343

  Fly   227 PAPAPPPPPPLPTPPAVVTVPPATPPPQRFDPRSQISSVVCG--REGS--TTPFIVRGNEFPRGQ 287
            ....|..|.|   .|:.|.:|....|          |...|.  |.|.  .|..|:.|....||.
  Fly   344 AETRPTTPNP---NPSRVNLPEKERP----------SVAACEKIRSGGKPLTVHILDGERVDRGV 395

  Fly   288 YPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCVHRMTEDRVVVGLGRYDLDDYGEDGAEMRN 352
            ||.::|:.:....:.||:|.||||:|..|::|||||:........|.||..:::: .|.|.:..|
  Fly   396 YPHMAAIAYNSFGSAAFRCGGSLIASRFVLTAAHCVNSDDSTPSFVRLGALNIEN-PEPGYQDIN 459

  Fly   353 VMRLLWHPDY--NTRSYSDADIALITIERPVTFNDIIAPICMWTVEASRTVSTTGFIAGWGRDED 415
            |:.:..||||  :::.|   |||::.:......:|:|.|.|::|..:....:...|:||||....
  Fly   460 VIDVQIHPDYSGSSKYY---DIAILQLAEDAKESDVIRPACLYTDRSDPPANYKYFVAGWGVMNV 521

  Fly   416 SSRTQYPRVVEAEI-------------ASPTVCASTWRGTMVTERSLCAGNRD-GSGPCVGDSGG 466
            ::|.....::.|.:             ..|:...:..||.:.::  |||.::: ....|.|||||
  Fly   522 TNRAVSKILLRAALDLVPADECNASFAEQPSANRTLRRGVIASQ--LCAADKNQRKDACQGDSGG 584

  Fly   467 GLMVKQGD---RWLLRGIVSAGERGPAGTCQLNQYVLYCDLSKHINWI 511
            .|:::..|   .:.:.|::|:|     ..|......||..:|..:::|
  Fly   585 PLILEIDDVDGTYSIVGVISSG-----FGCATKTPGLYTRVSSFLDYI 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	70/254 (28%)
		Tryp_SPc	277..511	CDD:214473	69/252 (27%)
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	384..627	CDD:214473	69/253 (27%)
		Tryp_SPc	385..630	CDD:238113	70/254 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437632
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840