DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp212 and AgaP_AGAP011325

DIOPT Version :9

Sequence 1:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_309327.4	Gene:	AgaP_AGAP011325 / 1270612	VectorBaseID:	AGAP011325	Length:	631	Species:	Anopheles gambiae

Alignment Length:	262	Identity:	73/262 - (27%)
Similarity:	137/262 - (52%)	Gaps:	13/262 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 VVCGREGSTTPFIV-RGNEFPRGQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCVHR--- 325
            :.|||....:.::: .|.:...|.:||.:|::::......::|.||::..:.:::|:|||:.
Mosquito    31 LTCGRRKVKSIYLIHNGVDAKAGHWPWHAAIFYRNKEHNEYECGGSILDHNTILTASHCVYTAGG 95

  Fly   326 -MTEDRVVVGLGRYDLDDYGEDGAEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIAP 389
             ::..||:|.:|:..|:...| ..::.||..::.||.:::.|... |||||.:...:|....:.|
Mosquito    96 VISATRVLVHVGQNHLEKASE-YTQIHNVRDIIVHPGFSSNSIIH-DIALIKLRTNITMTKYVQP 158

  Fly   390 ICMWTVEASR--TVSTTGFIAGWGRDEDSSRTQYPRVVEAEIASPTVCASTWR---GTMVTERSL 449
            :|:||:::.:  .|...|.|.|:|.:|....:|..:.....:.....|.::.|   ||.:|....
Mosquito   159 VCLWTMDSKQDLIVGKNGTIVGFGLNEQDVVSQQLKQALVGVVDALTCIASDRTVFGTHLTTDMF 223

  Fly   450 CAGNRDGSGPCVGDSGGGLMVKQGDRWLLRGIVS-AGERGPAGTCQLNQYVLYCDLSKHINWISE 513
            |...:.|...|.||||||:..:.|.:|.:||:|| ...||..|.|...:|..|.|::.::.||..
Mosquito   224 CGKGQKGVSACNGDSGGGMFFEIGGKWYVRGLVSFTPLRGNTGLCDPLKYTAYTDVAMYLEWIKP 288

  Fly   514 NI 515
            :|
Mosquito   289 HI 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	69/247 (28%)
		Tryp_SPc	277..511	CDD:214473	67/244 (27%)
AgaP_AGAP011325	XP_309327.4	Tryp_SPc	44..287	CDD:238113	68/244 (28%)
		Tryp_SPc	46..286	CDD:214473	67/241 (28%)
		Tryp_SPc	384..625	CDD:214473
		Tryp_SPc	385..625	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	145	1.000	Domainoid score	I9368
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9620
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X174
TreeFam	0	0.000	Not matched by this tool.
	4	3.910