Protein Alignment Fer1 and HAND2

DIOPT Version :9

• Sequence 1: NP_001262334.1
• Gene: Fer1 / 2768661
• FlyBaseID: FBgn0037475
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_068808.1
• Gene: HAND2 / 9464
• HGNCID: 4808
• Length: 217
• Species: Homo sapiens
• Alignment Length: 122
• Identity: 45/122 - (36%)
• Similarity: 62/122 - (50%)
• Gaps: 25/122 - (20%)

  Fly    75 PRRLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLS 139
            ||.:|       :|..||.:||||.||||.||..||..||.:|.:.:|||:.||:||.|||.:|.
Human    95 PRPVK-------RRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLM 152

  Fly   140 EMV-KKDKNGNEPGL--SLQRNYQKEPPKKIIL---------------KDRTGGVAH 178
            ::: |.|:||.....  .:::...||..:|..|               |.|||...|
Human   153 DLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQH 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fer1	NP_001262334.1	HLH	92..144	CDD:197674	27/52 (52%)
HAND2	NP_068808.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		12/27 (44%)
		bHLH_TS_HAND2	100..161	CDD:381477	31/60 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810