DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer1 and MSC

DIOPT Version :9

Sequence 1:	NP_001262334.1	Gene:	Fer1 / 2768661	FlyBaseID:	FBgn0037475	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_005089.2	Gene:	MSC / 9242	HGNCID:	7321	Length:	206	Species:	Homo sapiens

Alignment Length:	148	Identity:	43/148 - (29%)
Similarity:	70/148 - (47%)	Gaps:	29/148 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EGSQATNASTSSSDYFFGDEHSSESDDEDDAYSSGFNSDQENTEKTFCPFSR------------- 70
            |.|.|:.:..||::       ..:.|.|::..:.|.....|.     |...|
Human    35 ERSYASPSDNSSAE-------EEDPDGEEERCALGTAGSAEG-----CKRKRPRVAGGGGAGGSA 87

  Fly    71 ----RSHKPRRLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLA 131
                :...|.:...|.....||.|||.|||.||:.:::||..|:|.:|.:|.:.:|||:|||:||
Human    88 GGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLA 152

  Fly   132 ISYITFLSEMVKKDKNGN 149
            .|||..|.:::::|:..|
Human   153 SSYIAHLRQLLQEDRYEN 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer1	NP_001262334.1	HLH	92..144	CDD:197674	24/51 (47%)
MSC	NP_005089.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..115		18/91 (20%)
		Nuclear localization signal. /evidence=ECO:0000255	71..76		1/4 (25%)
		bHLH_TS_musculin	105..170	CDD:381546	29/64 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810