Protein Alignment Fer1 and TWIST1

DIOPT Version :10

• Sequence 1: NP_001262334.1
• Gene: Fer1 / 2768661
• FlyBaseID: FBgn0037475
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_000465.1
• Gene: TWIST1 / 7291
• HGNCID: 12428
• Length: 202
• Species: Homo sapiens
• Alignment Length: 64
• Identity: 35/64 - (54%)
• Similarity: 47/64 - (73%)
• Gaps: 1/64 - (1%)

  Fly    83 QMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMVKKDK 146
            ::..||..||:|||:|.||:||||..||..|||||.:| |||:.|||||..||.||.::::.|:
Human   105 ELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDFLYQVLQSDE 167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fer1	NP_001262334.1	bHLH_TS_PTF1A	87..142	CDD:381423	34/54 (63%)
TWIST1	NP_000465.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..105		35/64 (55%)
		bHLH_TS_TWIST1	98..174	CDD:381418	35/64 (55%)
		Sufficient for transactivation activity. /evidence=ECO:0000250	161..191		1/7 (14%)