Protein Alignment Fer1 and NEUROD2

DIOPT Version :9

• Sequence 1: NP_001262334.1
• Gene: Fer1 / 2768661
• FlyBaseID: FBgn0037475
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_006151.3
• Gene: NEUROD2 / 4761
• HGNCID: 7763
• Length: 382
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 76/300 - (25%)
• Similarity: 114/300 - (38%)
• Gaps: 79/300 - (26%)

  Fly    19 EGSQATNASTSSSDYFFGDEHSSESDDEDDAYSSGFNSDQENTEKTFCPFSRRSHKPRRLKCASQ 83
            ||::||.|.........|:|...|.::|      |.:..:....|...|..|:..|.|    ..:
Human    64 EGTEATLAEVKEEGELGGEEEEEEEEEE------GLDEAEGERPKKRGPKKRKMTKAR----LER 118

  Fly    84 MAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMVKKDKNG 148
            ...:||.||.|||.||..:|.|.:.||..:|.....::|||::||:||.:||..|||::   ::|
Human   119 SKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEIL---RSG 180

  Fly   149 NEP-----------GLS----------LQ---RNYQKE-----------------------PPKK 166
            ..|           |||          ||   ||:..|                       |..:
Human   181 KRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPYPYPCSR 245

  Fly   167 I------ILKDRTGGVAHSLSWYRKGDRYPGSKLYART--------WTPEDPRGPHSQPLPLYNN 217
            :      ......||.||:|..:.....|  ..|||..        :...:..||.|.||.|..|
Human   246 LAGAQCQAAGGLGGGAAHALRTHGYCAAY--ETLYAAAGGGGASPDYNSSEYEGPLSPPLCLNGN 308

  Fly   218 SNSNQNQN-SNQSSDDFS--GSGADMSDPGAAASIFSSGS 254
            .:..|:.: .::.|..:|  .|....|.|.....:|.|.:
Human   309 FSLKQDSSPDHEKSYHYSMHYSALPGSRPTGHGLVFGSSA 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fer1	NP_001262334.1	HLH	92..144	CDD:197674	23/51 (45%)
NEUROD2	NP_006151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129		19/74 (26%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	33/104 (32%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		1/5 (20%)
		Neuro_bHLH	180..310	CDD:403655	27/131 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910