DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer1 and Tal1

DIOPT Version :9

Sequence 1:	NP_001262334.1	Gene:	Fer1 / 2768661	FlyBaseID:	FBgn0037475	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_006502972.1	Gene:	Tal1 / 21349	MGIID:	98480	Length:	335	Species:	Mus musculus

Alignment Length:	213	Identity:	58/213 - (27%)
Similarity:	88/213 - (41%)	Gaps:	60/213 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ASTSSSDYFFGDEHSSESDDEDDAYSSGFNSDQENTEKTFCPFSRRSHKPRRLKCAS---QMAQQ 87
            ||..|.  |||         |.||:....|:::          .:|...|..::.:.   ....:
Mouse   151 ASLGSG--FFG---------EPDAFPMFTNNNR----------VKRRPSPYEMEISDGPHTKVVR 194

  Fly    88 RQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITFLSEMVK-KDKNGNE- 150
            |...|.|||.|.|::|.||..||..|||.|.:|:|||.:.|:||:.||.||::::. :::.|.:
Mouse   195 RIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQR 259

  Fly   151 --PGLSLQRNYQKEP-------------PKKIILKD---RTGGVAHSLSWYRKGDRY---PGSKL 194
              ||        |:|             |.:.:|:|   .......||......|.|   |..|.
Mouse   260 AKPG--------KDPVVGAGGGGAGGGIPPEDLLQDVLSPNSSCGSSLDGAASPDSYTEEPTPKH 316

  Fly   195 YARTWTP-----EDPRGP 207
            .:|:..|     .|..||
Mouse   317 TSRSLHPALLPAADGAGP 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer1	NP_001262334.1	HLH	92..144	CDD:197674	26/52 (50%)
Tal1	XP_006502972.1	bHLH_TS_TAL1	191..255	CDD:381549	27/63 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810