Protein Alignment GNA11 and cta

DIOPT Version :10

• Sequence 1: NP_002058.2
• Gene: GNA11 / 2767
• HGNCID: 4379
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_001036421.1
• Gene: cta / 3355131
• FlyBaseID: FBgn0000384
• Length: 457
• Species: Drosophila melanogaster
• Alignment Length: 365
• Identity: 161/365 - (44%)
• Similarity: 223/365 - (61%)
• Gaps: 24/365 - (6%)

Human     9 CC-----------LSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRII 62
            ||           .:.|..|.:..:.||:|.|.::|...||::||||||.||||||||:||||||
  Fly    91 CCGNIITYLVRLRSTPEELEQRYKSKEIDKFLEKEKHTFRRQVKLLLLGAGESGKSTFLKQMRII 155

Human    63 HGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILY---KYEQNKANALLI--REVDVEKVT 122
            ||..:..|....:..::|||:...||.::.|.|.|.|.:   ..||:..:|.|:  ..:||.|..
  Fly   156 HGVNFDYELLLEYQSVIYQNVIRGMQVLLDAREKLNIAWGSDGREQDAYDAKLMECNSLDVPKFM 220

Human   123 TFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTT 187
                :|...|..||:|.||:..::||||:|:|||..|:|.::.|:||..|:||.:|:|..|..|.
  Fly   221 ----EYAPPISRLWQDRGIRRAFERRREFQISDSVSYFLDEIQRLATPDYVPTHKDILHCRKATK 281

Human   188 GIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFE-NVTSIMFLVALSEYDQVLVESDNENRMEES 251
            |:.|:...::||.|..|||||||::|:||..||: :||||:|||:.||:||||.|....||:|||
  Fly   282 GVYEFCVKVQNIPFVFVDVGGQRTQRQKWTRCFDSSVTSIIFLVSSSEFDQVLAEDRKTNRLEES 346

Human   252 KALFRTIITYPWFQNSSVILFLNKKDLLEDKIL--YSHLVDYFPEFDGPQRDAQAAREFILKMFV 314
            |.:|.||:....|:..|:||||||.||||.|:.  .:.:..|:|.|:|........:.|||:||:
  Fly   347 KNIFDTIVNNATFKGISIILFLNKTDLLEQKVCNPETDIRWYYPHFNGNPHSVLDVQNFILQMFM 411

Human   315 DLNPDSD-KIIYSHFTCATDTENIRFVFAAVKDTILQLNL 353
            .:...|. ..||.|||.|.||.||..||.:|||||||.||
  Fly   412 SVRRSSSISRIYHHFTTAIDTRNINVVFNSVKDTILQRNL 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNA11	NP_002058.2	G-alpha	40..353	CDD:206639	148/321 (46%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	41..54		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	178..186		3/7 (43%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	201..210		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	270..277		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	329..334		2/4 (50%)
cta	NP_001036421.1	G_alpha	112..455	CDD:214595	157/344 (46%)