Protein Alignment GNA11 and CG30054

DIOPT Version :10

• Sequence 1: NP_002058.2
• Gene: GNA11 / 2767
• HGNCID: 4379
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_001036538.3
• Gene: CG30054 / 246420
• FlyBaseID: FBgn0050054
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 237/352 - (67%)
• Similarity: 288/352 - (81%)
• Gaps: 0/352 - (0%)

Human     7 MACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEED 71
            |.||.|.|..|.:|||.||:||||.:|:.::|||||||||..||||||||||||||||:|||:||
  Fly     1 MHCCSSTEAMEKRRINEEIDKQLRLEKKRSKRELKLLLLGACESGKSTFIKQMRIIHGSGYSDED 65

Human    72 KRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQYVSAIKTLW 136
            |||:.|||:||||.|||:||:||:.|||.|...::...|.|:..:|.|.|||||..|::||||||
  Fly    66 KRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTFEDPYLNAIKTLW 130

Human   137 EDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIF 201
            .|.||||||||||||||:||.:|:|.|:.||....||||.||:||.|.||..|..|||:|:..:.
  Fly   131 HDAGIQECYDRRREYQLTDSTEYFLGDIGRIEQADYLPTNQDILRAREPTFNITVYPFELDGYVL 195

Human   202 RMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQN 266
            .||||.|||:|||||||.|.|||||:||.|||||||.::||:|:||:|||||||.||||:.||:|
  Fly   196 SMVDVAGQRTERRKWIHFFSNVTSIIFLAALSEYDQFMMESENDNRLEESKALFHTIITFEWFKN 260

Human   267 SSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCA 331
            :|:||||||.|:||:||:||||||||||:|||::||.||||::|:||..::.|:.|.||||||||
  Fly   261 ASIILFLNKMDVLEEKIMYSHLVDYFPEYDGPKQDAYAAREYVLRMFQSISLDTYKKIYSHFTCA 325

Human   332 TDTENIRFVFAAVKDTILQLNLKEYNL 358
            ||||||:||||||||||||.||||.||
  Fly   326 TDTENIKFVFAAVKDTILQCNLKESNL 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNA11	NP_002058.2	G-alpha	40..353	CDD:206639	213/312 (68%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	41..54		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	178..186		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	201..210		5/8 (63%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	270..277		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	329..334		4/4 (100%)
CG30054	NP_001036538.3	G-alpha	34..347	CDD:206639	213/312 (68%)