Protein Alignment GLRA2 and glra2

DIOPT Version :10

• Sequence 1: NP_002054.1
• Gene: GLRA2 / 2742
• HGNCID: 4327
• Length: 452
• Species: Homo sapiens
• Sequence 2: XP_004912302.1
• Gene: glra2 / 100494348
• XenbaseID: XB-GENE-958032
• Length: 488
• Species: Xenopus tropicalis
• Alignment Length: 490
• Identity: 418/490 - (85%)
• Similarity: 426/490 - (86%)
• Gaps: 40/490 - (8%)

Human     1 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDARIRPN 65
            ||||||.|||||.|...|||.|||||||:||:||||.|  .:|||||||||||||||||||||||
 Frog     1 MNRQLVKILTALLALIFETNKFRTAFCKEHDTRSGKSP--PMSPSDFLDKLMGRTSGYDARIRPN 63

Human    66 FKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKP 130
            |||||||||||||||||||:.||||||||||||||.|||.||:||||||||||||||||||||||
 Frog    64 FKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQTWNDPRLSYSEYPDDSLDLDPSMLDSIWKP 128

Human   131 DLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGY 195
            ||||||||||||||||||||||||.|||.|||||||||||||||||||||||||||.||||||||
 Frog   129 DLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGY 193

Human   196 TMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQ 260
            |||||||||||..|||||:||||||||||||.|||||||||||||||||||||||||||||||||
 Frog   194 TMNDLIFEWLSTSPVQVADGLTLPQFILKEENELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQ 258

Human   261 MYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCL 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   259 MYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCL 323

Human   326 LFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK------------------------------ 360
            |||||||||||||||||||||||||||||||||:|
 Frog   324 LFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQSKTVLVGNESVESVRRMNGLRSTDSSAYGTLN 388

Human   361 --------EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKR 417
                    ||||.||||||||||||||||||||||||||||..|.|..|||.|:|||||||||||
 Frog   389 QIYNPSLREEDVARESRFNFSGYGMGHCLQVKDGTAVKATPPIPPPPQPKDADSIKKKFVDRAKR 453

Human   418 IDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 452
            |||||||||||||||||||||||||||||||||||
 Frog   454 IDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GLRA2	NP_002054.1	LIC	46..441	CDD:273305	373/432 (86%)
glra2	XP_004912302.1	LIC	44..477	CDD:273305	373/432 (86%)