DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Magel2 and MAGE

DIOPT Version :9

Sequence 1:	NP_038807.4	Gene:	Magel2 / 27385	MGIID:	1351648	Length:	1284	Species:	Mus musculus
Sequence 2:	NP_649702.2	Gene:	MAGE / 40860	FlyBaseID:	FBgn0037481	Length:	232	Species:	Drosophila melanogaster

Alignment Length:	222	Identity:	59/222 - (26%)
Similarity:	107/222 - (48%)	Gaps:	13/222 - (5%)

- Green bases have known domain annotations that are detailed below.

Mouse  1030 SVSRGSSAAQEDPDRES-QPLSPLDERANALVQFLLVKDQAKVPVQLSEMVNVVIREYKDDSLDI 1093
            |.||.:.:....|.:|: ||:..:|.:..|::.::|.....|:|::..:::.|.     .|..::
  Fly     3 STSRAARSQNAIPSQEAQQPVDVVDAKVRAILNYILDHTAQKIPIKDKDLIAVA-----GDKSEL 62

Mouse  1094 INR---ANTKLECTFGCQLKEVDTKTHTYIIVNKMAYPQCNLLASYLERPKFSLLMVVLSLIFMK 1155
            ..|   ....|..|||..|..:|..|.|:|...:......:.|.. .:||:|:||.::|..||::
  Fly    63 KKRLPLVTNLLAETFGIILTPLDATTKTFICTAEEPVASIHELTP-AQRPQFTLLYIILMYIFLR 126

Mouse  1156 GYCIRENLLFSFLFQLGLDVQETSGLFRIT-KKLITSVFVRHRYL--EYRQIPFTEPAEYELLWG 1217
            |..|.::.|:..|..|.:...|..|.|... :|.|...||:.:||  |..|:...:.::...|||
  Fly   127 GNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWG 191

Mouse  1218 PRAFLETNRVHILRFLAALYENQPQIW 1244
            |||..|.....:::|.:.|....|:::
  Fly   192 PRAKAEFTFEQMVQFASKLLNQHPKVF 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Magel2	NP_038807.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	114..208
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	406..431
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	673..717
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	747..792
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	839..860
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	913..964
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	985..1051		7/21 (33%)
		MAGE	1059..1223	CDD:279759	46/169 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1261..1284
MAGE	NP_649702.2	MAGE	36..201	CDD:279759	47/170 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842088
Domainoid	1	1.000	53	1.000	Domainoid score	I11275
eggNOG	1	0.900	-	-		E1_KOG4562
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1195799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42492
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11736
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.810