DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Akr1c13 and CG2767

DIOPT Version :9

Sequence 1:	XP_006516545.1	Gene:	Akr1c13 / 27384	MGIID:	1351662	Length:	324	Species:	Mus musculus
Sequence 2:	NP_649757.1	Gene:	CG2767 / 40946	FlyBaseID:	FBgn0037537	Length:	329	Species:	Drosophila melanogaster

Alignment Length:	319	Identity:	115/319 - (36%)
Similarity:	190/319 - (59%)	Gaps:	15/319 - (4%)

- Green bases have known domain annotations that are detailed below.

Mouse    19 DGEKEDLVKINV--PKSKSLEAAC-LALDVGYRHVDTAYAYQVEEEIGQAIQSKIKAGVVKREDL 80
            :|||..::.|..  ...:.:|.|. .||:.||||:|||..|..|:.||:.::..:.||.||||:|
  Fly    11 NGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKVKREEL 75

Mouse    81 FITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMK-SGDNDFPVNEQGKSLLD-TV 143
            ||.||:.....||..|:|.::|||:.|||||||||::|.|..:. :.|..|.::::|...:| |.
  Fly    76 FIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGLMEVDVTT 140

Mouse   144 DFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCE 208
            :....|..:|...:.||.||||||||:..|:.|:|.  ..|.:|..||:|.|:||.||.|:|:|:
  Fly   141 NHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLK--NCKIRPANNQIEHHVYLQQRDLVDFCK 203

Mouse   209 SKDIVLVAYGALGTQRYKEW-----VDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIVP 268
            |::|.:.||..||::...::     :.::.|.|::.|.:.::|..:.::||.:.||::|..|:..
  Fly   204 SENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDTGVSA 268

Mouse   269 LAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYLPAEF---LVDHPEYPFVEEY 324
            :.:|.....:::||.||.|:|:.|::..|..|::|.|.....|   :..|||:.|..:|
  Fly   269 IPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHPEFTFKNQY 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akr1c13	XP_006516545.1	AKR_AKR1C1-35	30..309	CDD:381334	105/288 (36%)
CG2767	NP_649757.1	ARA1	5..302	CDD:223729	107/292 (37%)
CG2767	NP_649757.1	Tas	10..297	CDD:223739	105/287 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930