Protein Alignment GLI2 and CG11902

DIOPT Version :10

• Sequence 1: XP_054197371.1
• Gene: GLI2 / 2736
• HGNCID: 4318
• Length: 1670
• Species: Homo sapiens
• Sequence 2: NP_651389.3
• Gene: CG11902 / 43070
• FlyBaseID: FBgn0028647
• Length: 1426
• Species: Drosophila melanogaster
• Alignment Length: 195
• Identity: 63/195 - (32%)
• Similarity: 98/195 - (50%)
• Gaps: 38/195 - (19%)

Human   494 SQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHG--------- 549
            :::|..|..::...|:.|.|.:|.    .|..  ||::|:.:::|..|:  :..||
  Fly  1199 TEDQELDESKEASGDEPKTEGQVF----QCGL--CTRKYNRKDRLTAHL--KKFHGPDCKPSTAK 1255

Human   550 ---------EKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLK 605
                     |.|.|:|.:  |   .|...:...|::||||||||||.||  |.|:.|:.|..:|:
  Fly  1256 TPNRPISPKEPKRFLCAF--C---GKAVSSSSNLIIHMRRHTGEKPFKC--EYCTMAFPRSSDLQ 1313

Human   606 THLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVK 670
            .|.|:||||:|:||  ..|.|.|:.:....:|. |.||.|:||.|..  |.|.:|..:.|..|::
  Fly  1314 CHRRTHTGERPHVC--TVCQKGFARSYKLQQHM-RIHSGERPYKCTY--CEKSFTQSNDLTLHIR 1373

Human   671  670
              Fly  1374  1373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GLI2	XP_054197371.1	PRK12323	<19..166	CDD:481241
		SFP1	<583..673	CDD:227516	36/88 (41%)
		C2H2 Zn finger	589..611	CDD:275368	8/21 (38%)
		C2H2 Zn finger	619..642	CDD:275368	6/22 (27%)
		C2H2 Zn finger	650..671	CDD:275368	6/21 (29%)
		PHA03247	<996..1473	CDD:223021
CG11902	NP_651389.3	zf-AD	6..83	CDD:462262
		C2H2 Zn finger	208..228	CDD:275370
		C2H2 Zn finger	236..256	CDD:275370
		C2H2 Zn finger	384..405	CDD:275368
		C2H2 Zn finger	417..437	CDD:275368
		C2H2 Zn finger	447..463	CDD:275368
		C2H2 Zn finger	578..599	CDD:275368
		C2H2 Zn finger	610..629	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		SUF4-like	673..>726	CDD:411020
		C2H2 Zn finger	676..703	CDD:411020
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	706..726	CDD:411020
		C2H2 Zn finger	706..726	CDD:275368
		C2H2 Zn finger	762..782	CDD:275368
		C2H2 Zn finger	866..887	CDD:275368
		C2H2 Zn finger	896..918	CDD:275368
		C2H2 Zn finger	926..947	CDD:275368
		C2H2 Zn finger	967..987	CDD:275368
		C2H2 Zn finger	996..1016	CDD:275368
		C2H2 Zn finger	1044..1063	CDD:275368
		C2H2 Zn finger	1224..1244	CDD:275368	6/23 (26%)
		C2H2 Zn finger	1271..1291	CDD:275368	7/24 (29%)
		zf-H2C2_2	1283..1306	CDD:463886	15/24 (63%)
		C2H2 Zn finger	1299..1319	CDD:275368	8/21 (38%)
		C2H2 Zn finger	1327..1347	CDD:275368	6/22 (27%)
		zf-H2C2_2	1340..1364	CDD:463886	10/26 (38%)
		SFP1	<1349..1405	CDD:227516	9/27 (33%)
		C2H2 Zn finger	1355..1375	CDD:275368	6/21 (29%)
		C2H2 Zn finger	1383..1401	CDD:275368