Protein Alignment TOR1B and CG4880

DIOPT Version :10

• Sequence 1: NP_055321.1
• Gene: TOR1B / 27348
• HGNCID: 11995
• Length: 336
• Species: Homo sapiens
• Sequence 2: NP_573177.1
• Gene: CG4880 / 32680
• FlyBaseID: FBgn0030803
• Length: 351
• Species: Drosophila melanogaster
• Alignment Length: 344
• Identity: 63/344 - (18%)
• Similarity: 122/344 - (35%)
• Gaps: 87/344 - (25%)

Human     3 RAGWLRGAAALALLLAARVVAAFEPITVGLAI---GAASAITGYL-----SYNDIYCRFAECCRE 59
            :|.| |..|.|.|.|||         .:|:.:   ...|.::|:|     .|:.|.......|..
  Fly    59 KAPW-RNWAYLILALAA---------GIGMLLQFTDKLSTVSGFLESYKNQYHSIVHNQDNYCNP 113

Human    60 ERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRNNKNPKKPLTLSLHGWAGTGKNFVSQIVAE 124
            .|.|  ..:.|....::..|.||...:..||....|.       .:.|.|.:|.||:..::|:.|
  Fly   114 SRRL--GDMVLHARHQVLNQDLALNQLELALDNTTNE-------AIVLVGTSGVGKSHTARILRE 169

Human   125 NL-HPKGLKSNFVHLFVSTLHFPHEQKIKLYQDQLQKWIRGNVSACANSVFIFDEMDKLHPGIID 188
            .. .|:.         |:||.:.....:...:..|     ..::.|..::.:.|.|.......:.
  Fly   170 TFPWPEN---------VNTLSWTGSSSLGRVKSML-----SGLTYCGQNMILIDNMTPKDAHFVP 220

Human   189 AIKPFLDYYEQ----VDGVSYRKAIFIFLSNAGGDLITKTALDFWRAGRKREDIQLKDLEPVLSV 249
            .|...:...|:    .:....::...:|:.|          ::..:.|.:.|    .|:| :|.
  Fly   221 IINEMISEGEKSANHTEHPQQKRLTIVFIFN----------VNSMQPGEEFE----MDME-ILR- 269

Human   250 GVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYRHVKMCVRAEMRARGSAIDEDIVTRVAEEMTFF 314
               |..|:.|              :.|..|:..|:..|:|.|.......::::.|..:.:.:.
  Fly   270 ---NMPHTQL--------------VTFATLDPTHLVDCIRREAAIAMVHLEDEHVEEIIKSID-- 315

Human   315 PRDEKIYSDKGCKTVQSRL 333
                  .|..|||::.:::
  Fly   316 ------ASASGCKSILAKV 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TOR1B	NP_055321.1	P-loop containing Nucleoside Triphosphate Hydrolases	55..176	CDD:476819	23/121 (19%)
		ClpA	<172..239	CDD:440308	8/70 (11%)
CG4880	NP_573177.1	P-loop containing Nucleoside Triphosphate Hydrolases	131..>181	CDD:476819	16/65 (25%)