Protein Alignment RPS6KA6 and CG4839

DIOPT Version :10

• Sequence 1: XP_016884912.1
• Gene: RPS6KA6 / 27330
• HGNCID: 10435
• Length: 762
• Species: Homo sapiens
• Sequence 2: NP_609349.1
• Gene: CG4839 / 34348
• FlyBaseID: FBgn0032187
• Length: 1003
• Species: Drosophila melanogaster
• Alignment Length: 319
• Identity: 109/319 - (34%)
• Similarity: 182/319 - (57%)
• Gaps: 15/319 - (4%)

Human    82 YEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRV-RTKMERDILV 145
            |.:...::.:.:..||.|:||:|.||....     |..|:|::||..:..:|:: ....|:::::
  Fly   686 YSQVAISELKKIATLGCGAFGRVDLVAYNQ-----QALALKIIKKIEVVKQDQIEHVYNEKNVMI 745

Human   146 EVNH-PFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQL 209
            :... ||||:|:..::.:..:|.:::...||||:|.:||...|.|:..||....:..|.|:||..
  Fly   746 KCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSH 810

Human   210 GIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWW 274
            ..:||||||||::|...|:.||.|||.:| .|.|.:|..:|.||.||:|||::..|||.::.|:|
  Fly   811 HFIYRDLKPENLMLGTDGYCKLVDFGFAK-FVRQNEKTNTFAGTPEYVAPEIILDRGHDRAVDYW 874

Human   275 SYGVLMFEMLTGTLPFQGKDRNETMNMILKA--KLGMPQFLSAEAQSLLRMLFKRNPANRLG--S 335
            :.|:|::|:|.|..||:|.::.:....||..  .:.||..:...||.|:|.|.|:.||.|||  .
  Fly   875 ALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQHLVRHLCKQLPAERLGYQR 939

Human   336 EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDP---EFTAKTPKDSPG 391
            :|:.:||||.:|.::||.:|..:::..|.|.......|...|.|   |...:.|::..|
  Fly   940 KGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTDLQYFGPSGVENDYEPPEELSG 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RPS6KA6	XP_016884912.1	STKc_RSK_N	94..408	CDD:270734	108/307 (35%)
		STKc_RSK4_C	438..732	CDD:271079
CG4839	NP_609349.1	CAP_ED	431..539	CDD:237999
		CAP_ED	550..663	CDD:237999
		STKc_cGK	700..957	CDD:270724	98/262 (37%)