Protein Alignment ANGPTL3 and CG9593

DIOPT Version :10

• Sequence 1: NP_055310.1
• Gene: ANGPTL3 / 27329
• HGNCID: 491
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_650493.2
• Gene: CG9593 / 41912
• FlyBaseID: FBgn0038365
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 374
• Identity: 101/374 - (27%)
• Similarity: 175/374 - (46%)
• Gaps: 51/374 - (13%)

Human   107 QVKNEEVKNMSLELNSKLESLLEEKILLQQ--KVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVE 169
            ::.|.::...|||     |.:|..|.|..|  |::.||..|..::.         :|..|...|.
  Fly    25 RIGNSDIGFKSLE-----ELVLIRKTLAAQALKLRGLEINLHRVLS---------KVVLLADAVV 75

Human   170 KQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRR--TSIQEPTEIS--LSSKPRAPRTTPFLQ 230
            :    :.....:.||....|:::.:.:.|..||..|  |::.|..|.|  :..:|...:|.| .:
  Fly    76 Q----VPGRYSSKEDPLAVLSERLNLLLERLNQEERISTNLLELKEWSTKVCQEPSPSQTLP-KE 135

Human   231 LNEIRNVK----HDGIPAECTTIYNRGEHTSGMYA-IRPSNSQV----FHVYCDVISGSP-WTLI 285
            |.|.::..    :....::|..: :.|....|:|. :.|..::|    :..||...:..| ||:|
  Fly   136 LTEEKDEPKVDFYQPAKSDCHEL-DEGVRVDGVYRFLVPERNEVQRDLYERYCAFATDGPAWTVI 199

Human   286 QHR---IDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEY 347
            |.|   .|..:|||.:|:.|:.|||.|..:||.|.|..:.|:.:.::.|||||::..:...:.||
  Fly   200 QSRGGSFDPHENFNRSWDEYRAGFGNLSRDFWFGNEFAHKILYRDDHELRIELQEAGEPLDWAEY 264

Human   348 S-FYLGNHETNYTLHLVA-ITGNVPNAIPENKDLVFSTWD----HKAKGHFNCPEGYSGGWWWHD 406
            . |:|.:...||.|.:.. ..|::|:|:.::..:.|||:|    |.......|.|.|.||||: |
  Fly   265 PLFWLDSESYNYQLSVAGEFRGSLPDALEQHNRMDFSTYDRRRNHAKSADSTCGEDYGGGWWF-D 328

Human   407 ECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTD 455
            .|.:.||||::...:..|.     .:.|.:........||::|:|.|.:
  Fly   329 RCTQCNLNGEHGVHQRASP-----AIIWMNWRTGTDKPKSSRMMIRPVN 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ANGPTL3	NP_055310.1	GumC	<81..>205	CDD:442439	22/99 (22%)
		FReD	243..453	CDD:238040	68/224 (30%)
CG9593	NP_650493.2	FReD	150..371	CDD:238040	68/227 (30%)