Protein Alignment ANGPTL3 and CG1791

DIOPT Version :10

• Sequence 1: NP_055310.1
• Gene: ANGPTL3 / 27329
• HGNCID: 491
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_572591.1
• Gene: CG1791 / 31927
• FlyBaseID: FBgn0030163
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 334
• Identity: 87/334 - (26%)
• Similarity: 148/334 - (44%)
• Gaps: 74/334 - (22%)

Human   134 LQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKE 198
            |..:|:::.::|.|                |||                     :||:....|:|
  Fly    57 LAARVQFMTDELQN----------------LKT---------------------ELNELQGLIEE 84

Human   199 IENQLR----RTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHDGIPAECTTIYNRGEHTSGM 259
            .:||..    .|.:..|...|:.:.|.|..|.|            |..|..|   |:. :|....
  Fly    85 YKNQGTGIPIATRLLRPLPASVQTFPLALATPP------------DDTPRNC---YDE-KHGQVR 133

Human   260 YAIRPSNSQVFHVYCD-VISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSI 323
            ..|.| :.:.|...|| .:....|.:|.:|.|||::||:.|:|||.|||.|:.||::||:|::.:
  Fly   134 IRIAP-DMEPFFASCDQKVRDGGWMVIAYRFDGSEDFNKDWQNYKAGFGALNSEFFIGLDKLHRL 197

Human   324 VKQSNYVLRIELEDWKDNKHYIEYS-FYLGNHETNYTLHLV-AITGNVPNAIPENKDLVFSTW-- 384
            ....::.|.|.::.....:.:..|. |.:|:....|.|::: |..|:..:::..:....|:|:
  Fly   198 TNSEHHELLIIMKKKSGEERFALYDHFSIGSESEKYLLYVLGAYKGDAGDSLRYHAGKKFTTFDQ 262

Human   385 DHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERR----RGLSWKS-QNGRLYSI 444
            |:...|. ||...::|.||:..||.|:||.|.:     :||..:.    :|:.||| ..|...|:
  Fly   263 DNDDNGQ-NCARTHAGAWWYGRECFESNLFGTF-----QSKYGQEIGYFKGILWKSFLPGPTGSL 321

Human   445 KSTKMLIHP 453
            ...:|||.|
  Fly   322 SYVRMLIRP 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ANGPTL3	NP_055310.1	GumC	<81..>205	CDD:442439	13/74 (18%)
		FReD	243..453	CDD:238040	65/219 (30%)
CG1791	NP_572591.1	FReD	119..331	CDD:238040	66/223 (30%)