Protein Alignment BHLHE22 and Oli

DIOPT Version :10

• Sequence 1: NP_689627.1
• Gene: BHLHE22 / 27319
• HGNCID: 11963
• Length: 381
• Species: Homo sapiens
• Sequence 2: NP_523592.1
• Gene: Oli / 35066
• FlyBaseID: FBgn0032651
• Length: 232
• Species: Drosophila melanogaster
• Alignment Length: 324
• Identity: 119/324 - (36%)
• Similarity: 147/324 - (45%)
• Gaps: 108/324 - (33%)

Human    40 PGMDLSLAPPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVPG-- 102
            ||:     |.....|...:::.||...|| |..:    ||.                  .|||
  Fly    11 PGL-----PNHGHMPIPPTANMLGGQHPA-PTAS----PPQ------------------SVPGRR 47

Human   103 LLVGSAGVGGDPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADP 167
            ..:||.|:|                        |..|:..|..|.|..|.:       :.|.:.|
  Fly    48 TPLGSVGLG------------------------GFYAQGMGMSQQPPTDEN-------KPGPSAP 81

Human   168 R--ASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSS 230
            .  .||.|....|.|.                     .||..:.:.||||..||||.||
  Fly    82 EKPLSPTAAAIAAIAI---------------------SGGTTTVAVSSGGASGSGSNSG------ 119

Human   231 SSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILM 295
               .:|:::.|.:|||||||||||||||||||||||:||||||||||||||||||||||||||||
  Fly   120 ---KQKNRQGKTVRLNINARERRRMHDLNDALDELRSVIPYAHSPSVRKLSKIATLLLAKNYILM 181

Human   296 QAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPAL-GAYEQAAGYPFSAGLPPAAS 358
            |..||||:|||:||:   |:.:.|: |....|..|||.|...| |.:.:          ||.:|
  Fly   182 QQNALEELRRLLAYI---QSTTGAA-PLDLGAFPAAAKLQALLQGPHNE----------PPTSS 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BHLHE22	NP_689627.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..94		11/53 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	135..154		6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..242		13/53 (25%)
		bHLH_TS_bHLHe22_bHLHb5	243..312	CDD:381524	61/68 (90%)
Oli	NP_523592.1	bHLH_TS_bHLHe22_bHLHb5	129..198	CDD:381524	61/71 (86%)