DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBMX and rbmx-2

DIOPT Version :9

Sequence 1:	NP_002130.2	Gene:	RBMX / 27316	HGNCID:	9910	Length:	391	Species:	Homo sapiens
Sequence 2:	NP_495237.1	Gene:	rbmx-2 / 183040	WormBaseID:	WBGene00016245	Length:	302	Species:	Caenorhabditis elegans

Alignment Length:	111	Identity:	34/111 - (30%)
Similarity:	56/111 - (50%)	Gaps:	16/111 - (14%)

- Green bases have known domain annotations that are detailed below.

Human    10 LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSL 74
            ::||||:...:|..:.|||.:||.::.:.|::|::|.||:||||:.::.......|..:.||.||
Worm    40 IYIGGLSYALSEGDVIAVFSQYGEVMNINLIRDKDTGKSKGFAFLCYKDQRSTILAVDNFNGISL 104

Human    75 DGKAIKVEQA---------------TKPSFESGRRGPPPPPRSRGP 105
            ..:.|:|:..               ||..:|.| ..|.|..|...|
Worm   105 HKRMIRVDHVEEYKVPKYKEDADDETKRLWEEG-CAPKPVMREAAP 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBMX	NP_002130.2	RRM_RBMX_like	7..86	CDD:409816	26/90 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	61..391		15/60 (25%)
		dnaA	165..>306	CDD:237605
		RBM1CTR	173..217	CDD:400429
		Necessary for the association to nascent RNAPII transcripts and nuclear localization	186..236
		Necessary for RNA-binding	333..391
rbmx-2	NP_495237.1	RRM_ist3_like	29..117	CDD:240857	26/76 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910