DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RAB30 and RabX4

DIOPT Version :9

Sequence 1:	NP_001272988.1	Gene:	RAB30 / 27314	HGNCID:	9770	Length:	203	Species:	Homo sapiens
Sequence 2:	NP_733043.1	Gene:	RabX4 / 42960	FlyBaseID:	FBgn0051118	Length:	213	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	76/173 - (43%)
Similarity:	113/173 - (65%)	Gaps:	2/173 - (1%)

- Green bases have known domain annotations that are detailed below.

Human     5 DYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQE 69
            |:...:|::::|::.|||||:|.|:....:.....:|||:||..|.:.::|..:|||||||||||
  Fly     4 DFVATYKVLVLGDSNVGKTCIVHRYCDEKYYDTYISTIGIDFKQKLINLDGVPIKLQIWDTAGQE 68

Human    70 RFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDL-AERREVS 133
            |||::|.:|||.|..::|.||:|..||:..|..|||.|::.||..|:.||.|||.:. |.:|.|.
  Fly    69 RFRTLTTAYYRGAMGILLMYDVTNLESYNNLSYWLRNIQENASPDVVKVLAGNKCECSATQRMVD 133

Human   134 QQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQ 176
            ::|.|:.:|..||.:.|.|.|.:.|:|..||.|| |.|.|.|:
  Fly   134 KERGEKIAENFDMPFFEVSCKSNINIEDAFLSLA-RKIREQRE 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RAB30	NP_001272988.1	Rab30	3..171	CDD:133314	73/166 (44%)
RAB30	NP_001272988.1	Effector region. /evidence=ECO:0000250	38..46		3/7 (43%)
RabX4	NP_733043.1	RAB	9..170	CDD:197555	72/161 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920