DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RAB30 and Rab1

DIOPT Version :9

Sequence 1:	NP_001272988.1	Gene:	RAB30 / 27314	HGNCID:	9770	Length:	203	Species:	Homo sapiens
Sequence 2:	NP_732610.1	Gene:	Rab1 / 42524	FlyBaseID:	FBgn0285937	Length:	205	Species:	Drosophila melanogaster

Alignment Length:	199	Identity:	88/199 - (44%)
Similarity:	131/199 - (65%)	Gaps:	3/199 - (1%)

- Green bases have known domain annotations that are detailed below.

Human     5 DYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQE 69
            :||:|||::|||::||||:||:.||....:.....:||||||.|:|:|::|:.:|||||||||||
  Fly     7 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71

Human    70 RFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQ 134
            |||:||.||||.|:.:|:.||.|.:|||..:.:||.|||:||...|..:|||||.||..::.|..
  Fly    72 RFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDH 136

Human   135 QRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISE-ARQNTLVNNVSSPLPGEGKSISYLT 198
            ..|.|::....:.:||||||.:.|||:.|:.:|..:.:. ...::..:|.|.....:|:.:....
  Fly   137 TTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTK 201

Human   199 --CC 200
              ||
  Fly   202 SGCC 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RAB30	NP_001272988.1	Rab30	3..171	CDD:133314	83/165 (50%)
RAB30	NP_001272988.1	Effector region. /evidence=ECO:0000250	38..46		4/7 (57%)
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	81/164 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920