Protein Alignment RAB30 and RabX6

DIOPT Version :10

• Sequence 1: NP_055303.2
• Gene: RAB30 / 27314
• HGNCID: 9770
• Length: 203
• Species: Homo sapiens
• Sequence 2: NP_001261219.1
• Gene: RabX6 / 38084
• FlyBaseID: FBgn0035155
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 173
• Identity: 63/173 - (36%)
• Similarity: 95/173 - (54%)
• Gaps: 11/173 - (6%)

Human    11 KIVLIGNAGVGKTCLVRRFTQGLF--PPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQERFRS 73
            |::|.|:.||||:.|.|||....|  ...:.:|:|:|.:.:...:|.:::|||:|||.|.||..|
  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGMERVAS 74

Human    74 ITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERR-EVSQQRA 137
            :|.|||:.|...||.:.:....||..|.:.|.:|..||.|..| .:.|||.||..|. |||.:..
  Fly    75 VTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYAENAKI-FICGNKSDLDGREPEVSDEEV 138

Human   138 EEFSEAQDMYYL-----ETSAKESDNVEKLFLDLACRLISEAR 175
            |.|.|  ..:.|     :||.:....||::|.|::.:|:...|
  Fly   139 EAFCE--QCHSLISATYKTSCRSGAGVEEMFRDISRQLVHANR 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB30	NP_055303.2	Rab30	3..171	CDD:133314	61/167 (37%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	36..44		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		8/15 (53%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	61/164 (37%)