Protein Alignment RAB30 and Rab2

DIOPT Version :10

• Sequence 1: NP_055303.2
• Gene: RAB30 / 27314
• HGNCID: 9770
• Length: 203
• Species: Homo sapiens
• Sequence 2: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 211
• Identity: 86/211 - (40%)
• Similarity: 130/211 - (61%)
• Gaps: 16/211 - (7%)

Human     6 YDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQER 70
            |.:|||.::||:.||||:||:.:||...|.|....||||:|..:.:.|:|:::|||||||||||.
  Fly     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEA 67

Human    71 FRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQ 135
            |||||:||||.|...:|.||||..|:|..|..||.:..|::::.::.:|:|||.||..||||.::
  Fly    68 FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKE 132

Human   136 RAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTL-VNNVS---------SP---- 186
            ..|.|:....:.::||||:.:.|||:.|::.|..:..:.::... :||.:         ||
  Fly   133 EGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNPS 197

Human   187 LPGEGKSISYLT--CC 200
            |||.|.:.....  ||
  Fly   198 LPGAGGAAGAANSGCC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB30	NP_055303.2	Rab30	3..171	CDD:133314	76/164 (46%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	36..44		3/7 (43%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		12/15 (80%)
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	84/209 (40%)