Protein Alignment RAB30 and Rab35

DIOPT Version :10

• Sequence 1: NP_055303.2
• Gene: RAB30 / 27314
• HGNCID: 9770
• Length: 203
• Species: Homo sapiens
• Sequence 2: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 182
• Identity: 83/182 - (45%)
• Similarity: 121/182 - (66%)
• Gaps: 9/182 - (4%)

Human     6 YDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQER 70
            :|.|||:::||::||||:.|:.||:...|......||||||.|:||:|.|.:|||||||||||||
  Fly     5 FDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQER 69

Human    71 FRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQ 135
            ||:||.:|||..:.:|:.||:|..|||..:..||.|| |...:.|..||||||.|..:|:.|..:
  Fly    70 FRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEI-QNNCDVVKKVLVGNKNDDPDRKVVITE 133

Human   136 RAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLI--------SEARQNTL 179
            .|:.|::..|:...|||||::.|||.:||.:..:::        :|.:::||
  Fly   134 DAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTL 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB30	NP_055303.2	Rab30	3..171	CDD:133314	80/164 (49%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	36..44		2/7 (29%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		11/15 (73%)
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	83/182 (46%)