DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RAB30 and RabX2

DIOPT Version :9

Sequence 1:	NP_001272988.1	Gene:	RAB30 / 27314	HGNCID:	9770	Length:	203	Species:	Homo sapiens
Sequence 2:	NP_572627.1	Gene:	RabX2 / 31971	FlyBaseID:	FBgn0030200	Length:	195	Species:	Drosophila melanogaster

Alignment Length:	188	Identity:	69/188 - (36%)
Similarity:	114/188 - (60%)	Gaps:	4/188 - (2%)

- Green bases have known domain annotations that are detailed below.

Human     3 MEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAG 67
            |..:|:|||::::|::||||:||:.||:...|......|:|:|...::||:....:.||:|||:|
  Fly     1 MSHFDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSG 65

Human    68 QERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREV 132
            .:||.|:..|.||||:.::|.||||..:||:.:..|::||.:...:||..:|||||.|....|:|
  Fly    66 DKRFNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQV 130

Human   133 SQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNVSSPLPGE 190
            |.::...::....:.:.|.|||...||..:|..||    .:.....:::|..||:|.|
  Fly   131 SMEQGFNYAHRGALGFEEVSAKSGMNVYDIFSSLA----MDIYHRYVLHNPISPMPSE 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RAB30	NP_001272988.1	Rab30	3..171	CDD:133314	64/167 (38%)
RAB30	NP_001272988.1	Effector region. /evidence=ECO:0000250	38..46		2/7 (29%)
RabX2	NP_572627.1	RAB	8..171	CDD:197555	61/166 (37%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	59/156 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920