Protein Alignment HPGDS and GstE2

DIOPT Version :10

• Sequence 1: NP_055300.1
• Gene: HPGDS / 27306
• HGNCID: 17890
• Length: 199
• Species: Homo sapiens
• Sequence 2: NP_611324.1
• Gene: GstE2 / 37107
• FlyBaseID: FBgn0063498
• Length: 221
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 51/209 - (24%)
• Similarity: 80/209 - (38%)
• Gaps: 57/209 - (27%)

Human     5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTL----PFGKIPILEVDGLTLHQSL 65
            |||.     ||..:.|.:..:|:...||         .|...    |...:|:||.:|..:..|.
  Fly    20 KLTL-----RALNLDYEYKEMDLLAGDH---------FKDAFLKKNPQHTVPLLEDNGALIWDSH 70

Human    66 AIARYLTKN---------TDLAGNTEMEQ-CHVDAIVDTLDDFMS----CFPWAEKKQDV--KEQ 114
            ||..||...         .||....:::| ...||.:    .|||    ..|:..::..:  ||:
  Fly    71 AIVCYLVDKYANSDELYPRDLVLRAQVDQRLFFDASI----LFMSLRNVSIPYFLRQVSLVPKEK 131

Human   115 MFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRK 179
            :.|....|.      .|:.:||...:|.|:.:|.||......:::|..    :||    |..|:
  Fly   132 VDNIKDAYG------HLENFLGDNPYLTGSQLTIADLCCGATASSLAA----VLD----LDELK- 181

Human   180 KVQAIPAVANWIKR 193
                .|.||.|.:|
  Fly   182 ----YPKVAAWFER 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPGDS	NP_055300.1	GST_N_Sigma_like	4..73	CDD:239337	20/71 (28%)
		GST_C_Sigma	82..181	CDD:198328	24/105 (23%)
GstE2	NP_611324.1	GstA	5..200	CDD:440390	51/209 (24%)