Protein Alignment HPGDS and GstS1

DIOPT Version :10

• Sequence 1: NP_055300.1
• Gene: HPGDS / 27306
• HGNCID: 17890
• Length: 199
• Species: Homo sapiens
• Sequence 2: NP_001261040.1
• Gene: GstS1 / 36927
• FlyBaseID: FBgn0010226
• Length: 250
• Species: Drosophila melanogaster
• Alignment Length: 205
• Identity: 76/205 - (37%)
• Similarity: 121/205 - (59%)
• Gaps: 11/205 - (5%)

Human     3 NYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAI 67
            :|.|.|||::..||.:||:|||.:.:|||.|:.:.:||.:|.|:|.|::|:|||||..:|||:::
  Fly    49 SYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDEWPALKPTMPMGQMPVLEVDGKRVHQSISM 113

Human    68 ARYLTKNTDLAGNTEMEQCHVDAIVDTLDDF---MSCFPWAEKKQDVKEQMFNELLTYNA---PH 126
            ||:|.|...|.|.|..|...:|.:|||::||   ...|...|.:.::||:   :|:|.||   |.
  Fly   114 ARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLSSEQFVSYEPEDEIKEK---KLVTLNAEVIPF 175

Human   127 LMQDLD-TYLGGREWLIGNSVTWADFYWE-ICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVAN 189
            .::.|: |.......|....:||||.|:. |......:.|.|||:.:|.|..:...|.|:..:..
  Fly   176 YLEKLEQTVKDNDGHLALGKLTWADVYFAGITDYMNYMVKRDLLEPYPALRGVVDAVNALEPIKA 240

Human   190 WIKRRPQTKL 199
            ||::||.|::
  Fly   241 WIEKRPVTEV 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPGDS	NP_055300.1	GST_N_Sigma_like	4..73	CDD:239337	34/68 (50%)
		GST_C_Sigma	82..181	CDD:198328	31/106 (29%)
GstS1	NP_001261040.1	GST_N_Sigma_like	50..119	CDD:239337	34/68 (50%)
		GST_C_Sigma_like	129..232	CDD:198301	31/105 (30%)