DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBMXL2 and Rox8

DIOPT Version :9

Sequence 1:	NP_055284.3	Gene:	RBMXL2 / 27288	HGNCID:	17886	Length:	392	Species:	Homo sapiens
Sequence 2:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	125	Identity:	41/125 - (32%)
Similarity:	65/125 - (52%)	Gaps:	23/125 - (18%)

- Green bases have known domain annotations that are detailed below.

Human    10 LFIGGLNLETDEKALEAEFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKAAARDMNGKSL 74
            :|:|.|:.|.:.:.|...|..:|.|....:::|..|.||:|:|||:|...|:|:.|.:.|||:.:
  Fly    97 IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWI 161

Human    75 DGKAIKVAQATKPAFESSRRGPPPPR--SRGRPRFLRGTRGGGGGPRRSPSRGGPDDDGG 132
            ..::|:...:|        |..||||  |:|      |.:|||.|       |||.:..|
  Fly   162 GSRSIRTNWST--------RKLPPPREPSKG------GGQGGGMG-------GGPGNGSG 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBMXL2	NP_055284.3	RRM_RBMX_like	7..86	CDD:240828	24/75 (32%)
		RRM	<9..>81	CDD:223796	24/70 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..392		21/68 (31%)
		RBM1CTR	173..217	CDD:285341
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	41/125 (33%)
		RRM1_TIA1_like	9..80	CDD:240798
		RRM2_TIA1_like	96..170	CDD:240799	24/72 (33%)
		RRM3_TIA1_like	221..294	CDD:240800
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910