Protein Alignment ERLEC1 and CG6766

DIOPT Version :10

• Sequence 1: NP_056516.2
• Gene: ERLEC1 / 27248
• HGNCID: 25222
• Length: 483
• Species: Homo sapiens
• Sequence 2: NP_609537.1
• Gene: CG6766 / 34619
• FlyBaseID: FBgn0032398
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 517
• Identity: 169/517 - (32%)
• Similarity: 254/517 - (49%)
• Gaps: 87/517 - (16%)

Human    18 LLVLCGLLEASGGGRALPQLSDDIPFRVNWPGTEFSLPTTGVLYKEDNYV-IMTTAHKEKYKCIL 81
            :.:|..|:.|:....| ....|.|.:::     :|.:|...|.....|.: ...|..||||.|::
  Fly    11 IALLLNLIIAAVSHEA-KDFDDSILYKI-----DFEVPDLDVQPSLGNQLRTFYTPDKEKYDCLI 69

Human    82 PLVTSGDEEEEKDYKGPNPRELLEPLFKQSSCSYRIESYWTYEVCHGKHIRQYHEEKETGQKINI 146
            |.:....|||:.|....:|..||:|:|...:|:||||:||:||:|||.|:||||||:| |:.:..
  Fly    70 PTLEHQKEEEKSDKPELSPITLLQPIFSALTCTYRIEAYWSYEICHGHHVRQYHEERE-GKNVKF 133

Human   147 HEYYLGNMLAKNL-----LFEKEREAEEKEKSNEIPTKNIEGQMTPYYPVGMGNGTPCSLKQNRP 206
            .|||||....:.:     .::.:.:|..|.|...:   .|:....||:.:...:||.|.: .|.|
  Fly   134 QEYYLGKWTDEKMEILTKAWQADIKAGVKPKYKSL---KIDNTRYPYFEMEYSDGTMCDI-INAP 194

Human   207 RSSTVMYICHPESKHEILSVAEVTTCEYEVVILTPLLCSHPKYRFRASPVND--IFCQSLPGSPF 269
            |::.|.|:|:|..|::|.|..|.::|.||.:||:..||  |.....|....:  |.|.:....|.
  Fly   195 RTTMVRYVCYPHGKNDIYSFKETSSCNYEAIILSSALC--PIRALHAEETKELSIQCFNSESKPH 257

Human   270 KPLTLRQLEQQEEILRVPFRRNKEEDLQSTKEER------------------------------- 303
            :||::.:.|.:|.:       ..|.||...||:.
  Fly   258 RPLSMLRSELKEWV-------ESEADLLVFKEKATENLWPKTDGDLVTLNYGGDMEKVLLEHFRN 315

Human   304 --------FPAIHKSIAIGSQPVLTVGTTHISKLTDDQLIKEFLSGSYCFRGGVGWWKYEFCYGK 360
                    |..:..|||...     .|.|.|:.||.   :|:|:||..|..||.||||||||||:
  Fly   316 GDLKVDGDFQQLLLSIAASE-----TGPTPITDLTP---LKDFISGKNCLTGGNGWWKYEFCYGR 372

Human   361 HVHQYHEDKDSGKTSVVVGTWNQEEHIEWAKKNTARAYHLQDDGTQT---VRMVSHFYGNGDICD 422
            ||.|:|:||.| :..:.:|.:::|.|..|:..|       .|.|.:.   ...:.|.||.|..|:
  Fly   373 HVRQFHKDKTS-EVELFLGYFSEEAHRAWSNAN-------PDKGARRSGFTTSIWHHYGKGTHCE 429

Human   423 ITDKPRQVTVKLKCKE-SDSPHAVTVYMLEPHSCQYILGVESPVICKILDTADENGLLSLPN 483
            ....||:|.|||.|.. ::|..||::|:|||.:|||||.||||.||.::..||..||:.|.|
  Fly   430 QIGVPREVDVKLTCTPVTNSGTAVSMYLLEPKTCQYILVVESPTICDLIHNADSQGLVKLEN 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERLEC1	NP_056516.2	PRKCSH	111..199	CDD:400321	34/92 (37%)
		PRKCSH	<206..250	CDD:414904	18/43 (42%)
		PRKCSH	342..421	CDD:400321	31/81 (38%)
CG6766	NP_609537.1	PRKCSH	100..188	CDD:400321	34/91 (37%)
		PRKCSH	354..428	CDD:400321	31/81 (38%)