DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GPR162 and dop-4

DIOPT Version :9

Sequence 1:	NP_062832.1	Gene:	GPR162 / 27239	HGNCID:	16693	Length:	588	Species:	Homo sapiens
Sequence 2:	NP_508238.2	Gene:	dop-4 / 183715	WormBaseID:	WBGene00016872	Length:	517	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	53/253 - (20%)
Similarity:	107/253 - (42%)	Gaps:	28/253 - (11%)

- Green bases have known domain annotations that are detailed below.

Human    17 ALSWLACGLLALLANAWIILSISAKQQKHKPLELLLCFLAGTHILMAAVPLTTFAVVQLRRQASS 81
            |::..:..||.:..|..:::::..|:....|...|:..||...:::..:.:...::.::     :
Worm    46 AIALFSICLLTVAGNCLVVIAVCTKKYLRNPTGYLIISLAIADLIVGVIVMPMNSLFEI-----A 105

Human    82 DYDW--NESICKVFVSTYYTLALATCFTVASLSYHRMWMVRWPVNYRLSNAKKQALHAVMGIWMV 144
            ::.|  ...:|.||.:.....:.|:.:.:..:|..|....:.|:.||...:|::.|.|::.:|::
Worm   106 NHTWLFGLMMCDVFHAMDILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVWVL 170

Human   145 SFILSTLPSIGWHNNGERYY--ARGCQFIVSKIGLGFGVCFSLLLLGGIVMGLVCVAITFYQTLW 207
            |.|||....|.|..:....|  ...|.|..||:    .|.||.|:...|.:.|:..|   |..::
Worm   171 SAILSFPGIIWWRTSSPHLYEDQSQCLFTDSKM----YVSFSSLVSFYIPLFLILFA---YGKVY 228

Human   208 ARPRRARQARRVG---------GGGGTKAGGPGALGTRPAFEVPAIVVEDARGKRRSS 256
            ....|..:..|:|         .|..:.......|.:.   ..|.:.:...|||:.||
Worm   229 IIATRHSKGMRMGIKTVSIKKRNGKKSNTETESILSSE---NEPTLRIHFGRGKQSSS 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GPR162	NP_062832.1	7tm_1	34..>207	CDD:278431	38/176 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	445..474
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	511..550
dop-4	NP_508238.2	7tm_4	53..>245	CDD:304433	44/203 (22%)
dop-4	NP_508238.2	7tm_1	59..463	CDD:278431	50/240 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910