Protein Alignment GPKOW and gpkow

DIOPT Version :10

• Sequence 1: XP_054182812.1
• Gene: GPKOW / 27238
• HGNCID: 30677
• Length: 491
• Species: Homo sapiens
• Sequence 2: XP_012823775.1
• Gene: gpkow / 496860
• XenbaseID: XB-GENE-943875
• Length: 498
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 229/493 - (46%)
• Similarity: 304/493 - (61%)
• Gaps: 55/493 - (11%)

Human    29 ASTAPISFGFTRTSARRRLADSGDGAGPSPEEKDFLKTVEGRELQSVKPQEAPKELVIPLIQNGH 93
            :|.||:||||:|:|.::.|..:||..  ..:||::|...||:||.|..|....||||||||.. :
 Frog    26 SSQAPVSFGFSRSSKKKFLVANGDER--EEDEKEYLVGAEGKELLSANPTPEAKELVIPLIHK-N 87

Human    94 RRQPPARPPGPSTDT--GALADGVVSQAVKELIAESKKSLEERENAGVDPTLAIPMIQKGCTP-- 154
            |...|.:......|.  |...:.|:||||||||.||:::||  :|:..|.||:||::.:...|
 Frog    88 RWSKPNKKKDNEEDAVPGTEEEAVLSQAVKELIEESRRTLE--DNSETDQTLSIPLLMQNRIPDG 150

Human   155 --SGEGADSEPRAETVPEEANYEAVPVEAYGLAMLRGMGWKPGEGIGRTFNQVVKPRVNSLRPKG 217
              .||..|...|.::. |.|:|:|||||.||:|||||||||.||||||||.|.|||....|||||
 Frog   151 YEDGEKVDVSLRPDSA-EAADYDAVPVEYYGMAMLRGMGWKEGEGIGRTFKQDVKPLEQKLRPKG 214

Human   218 LGLGANLTEAQALTPTGPSRMPRPDEEQEKDKEDQPQGLVPGGAVVVLSGPHRGLYGKVEGLDPD 282
            |||||:.:..:.|.|..|.:..:|.|:    .|::.:||..|.:|.:.||.|:.|||||||:|||
 Frog   215 LGLGADRSALKDLEPQKPRKPLKPGEK----LEEESRGLGKGSSVQIQSGAHKDLYGKVEGVDPD 275

Human   283 NVRAMVRLAVGSRVVTVSEYYLRPVSQQEFDKNTLDL------------------------RQQN 323
            |.|||::||:|.:|||||.:.||.||..|:.|...||                        ::::
 Frog   276 NSRAMIKLAIGGKVVTVSLFSLRLVSSAEYTKFAKDLSRLSKAHQESKEEQHKDRSPDKEQQRKD 340

Human   324 G---TASSRKTLWNQELYIQQDNSERKRKHLPDRQDGPAAKSEKAAPRSQHWLHRDLRVRFVDNM 385
            |   :.|||    |.:|   .:..:|.|:..|||:    .:.:|..|..|.||||||||||:|..
 Frog   341 GEKHSESSR----NSDL---NNREKRHRQRSPDRE----KEKKKIRPEPQGWLHRDLRVRFIDKN 394

Human   386 YKGGQYYNTKMIIEDVLSPDTCVCRTDEGRVLEGLREDMLETLVPKAEGDRVMVVLGPQTGRVGH 450
            ||||:|||:||.|||||||..|.|||:.||:|:.:|:|||||::||.||:.||||||...|.||.
 Frog   395 YKGGKYYNSKMFIEDVLSPTRCSCRTESGRILDDMRQDMLETIIPKEEGEHVMVVLGKYRGMVGK 459

Human   451 LLSRDRARSRALVQLPRENQVVE-LHYDAICQYMGPSD 487
            :|.||:.:|||||||..|:...| |.|||||.|.|..|
 Frog   460 ILHRDKQKSRALVQLQGEHDSAETLSYDAICHYTGAQD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPKOW	XP_054182812.1	G-patch_2	169..223	CDD:432700	40/53 (75%)
		KOW_GPKOW_A	259..315	CDD:240516	32/55 (58%)
		KOW_GPKOW_B	434..484	CDD:240517	29/50 (58%)
gpkow	XP_012823775.1	G-patch_2	163..222	CDD:432700	41/59 (69%)
		KOW_GPKOW_A	252..307	CDD:240516	32/54 (59%)
		KOW_GPKOW_B	443..494	CDD:240517	29/50 (58%)