Protein Alignment GPKOW and CG10324

DIOPT Version :10

• Sequence 1: XP_054182812.1
• Gene: GPKOW / 27238
• HGNCID: 30677
• Length: 491
• Species: Homo sapiens
• Sequence 2: NP_650571.2
• Gene: CG10324 / 42028
• FlyBaseID: FBgn0038454
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 482
• Identity: 123/482 - (25%)
• Similarity: 198/482 - (41%)
• Gaps: 125/482 - (25%)

Human    34 ISFGFTRTSARRRLADSGDGAGPSPEEK-DFLKTVEGRELQSV--KPQEAPKELVIPLIQNGHRR 95
            |||||::.|.:..:..|..   |..|.| :.:|.:||.|:..|  |.:.||  |.|.:|  |.::
  Fly     6 ISFGFSKLSKKPNILPSKQ---PKEESKVELIKCLEGNEIMPVDEKVEAAP--LTIKMI--GMQK 63

Human    96 QPPA--------------RPPGPSTDTGALADGVVSQAVKELIAES-KKSLEER---------EN 136
            ...|              ..|.|...|      .|:|::.|:.|.. .:|||:|         :|
  Fly    64 TSSALASLMRRRAVLLGEEEPDPEEVT------PVAQSIAEVTAGGPTESLEQRAARELISAIQN 122

Human   137 AGV----DPTLAIPMIQKGCTPSGEGADSEPRAETVPEEA---NYEAVPVEAYGLAMLRGMGW-- 192
            .|.    |..|.:|.:.....|. :||          :||   :|:.:|::.:||||||||||
  Fly   123 NGAEGLDDQKLVLPALSADELPL-DGA----------KEATLDDYDNIPIQQFGLAMLRGMGWVD 176

Human   193 ----KPGEGIGRTFNQVVKPRVNS--LRPKGLGLGANLTEAQALTPTGPSRMPRPDEEQEKDKED 251
                |.|.|          |..::  |||||:||||:    :||.|......|..:|..|..|:
  Fly   177 PPPKKKGSG----------PIDDAPFLRPKGMGLGAD----KALKPKALLVQPEKNEVLEIKKQ- 226

Human   252 QPQGLVPGGAVVVLSGPHRGLYGKVEGLDPDNVRAMVRLAVGSRVVTVSEYYLRPVSQQEFDKNT 316
                    ..|.:|.|..:..||:::|.|....|.:|::|:|......:|:..:|||::|:
  Fly   227 --------AYVRILGGKQKDQYGQIQGFDDHAGRVIVKMAIGGAKEAFNEFLCQPVSRKEY---- 279

Human   317 LDLRQQNG----TASSRKTLWNQ----ELYIQQDN------SERKRKHLPDRQDGPAAKSEKAAP 367
                .|.|    ||...:...|:    ::.::|:|      .:|:.:...||.:....||.|  |
  Fly   280 ----SQYGKCINTAKYEEFKKNENEHGQIIVKQENPSGRRDRDRREEIRSDRDEAQNQKSSK--P 338

Human   368 RSQHWLHRDLRVRFVDNMYKGGQYYNTKMIIEDVLSPDTCVCRTDEGRVLEGLREDMLETLVPKA 432
            ..|.....|.|::..:...:..:|.:.|            ..:.:..|..:..|:...|....|.
  Fly   339 GDQRSSKEDYRMKCKEEDKRSYKYEDKK------------TYKDEHRRTYKDERKSYKEAKSNKE 391

Human   433 EGDRVMVVLGPQTGRVGHLLSRDRARS 459
            |.||....:...:..|.....|:|.||
  Fly   392 EVDREKKYVRSGSSSVSKREERERRRS 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPKOW	XP_054182812.1	G-patch_2	169..223	CDD:432700	26/64 (41%)
		KOW_GPKOW_A	259..315	CDD:240516	16/55 (29%)
		KOW_GPKOW_B	434..484	CDD:240517	7/26 (27%)
CG10324	NP_650571.2	G-patch_2	148..205	CDD:432700	28/80 (35%)
		KOW_GPKOW_A	227..282	CDD:240516	16/62 (26%)
		MSCRAMM_ClfA	<325..507	CDD:468110	23/108 (21%)