Protein Alignment GPKOW and Gpkow

DIOPT Version :10

• Sequence 1: XP_054182812.1
• Gene: GPKOW / 27238
• HGNCID: 30677
• Length: 491
• Species: Homo sapiens
• Sequence 2: NP_776108.2
• Gene: Gpkow / 209416
• MGIID: 1859610
• Length: 488
• Species: Mus musculus
• Alignment Length: 481
• Identity: 359/481 - (74%)
• Similarity: 398/481 - (82%)
• Gaps: 14/481 - (2%)

Human    25 PLTAASTAPISFGFTRTSARRRLADSGDGAGPSPEEKDFLKTVEGRELQSVKPQEAPKELVIPLI 89
            |.:|.|.|||||||||||.||||||.||....:|||||||.|||||:||||.|.|||||||||||
Mouse     8 PPSAPSMAPISFGFTRTSVRRRLADLGDSERQAPEEKDFLATVEGRKLQSVNPPEAPKELVIPLI 72

Human    90 QNGHRRQPPARPPGPSTDTGA--LADGVVSQAVKELIAESKKSLEERENAGVDPTLAIPMIQKGC 152
            |||.||||.::.|.||::|..  ::|||:||||||||.||||||||||||||||||.||||||||
Mouse    73 QNGSRRQPLSKNPKPSSETSTVLMSDGVLSQAVKELIEESKKSLEERENAGVDPTLTIPMIQKGC 137

Human   153 TPSGEGADSEPRAETVPEEANYEAVPVEAYGLAMLRGMGWKPGEGIGRTFNQVVKPRVNSLRPKG 217
            ||..||:||||:||||||||:||||||||||||||||||||||:|||.||:|||||||||:||||
Mouse   138 TPIEEGSDSEPQAETVPEEADYEAVPVEAYGLAMLRGMGWKPGKGIGNTFSQVVKPRVNSIRPKG 202

Human   218 LGLGANLTEAQALTPTGPSRMPRPDEEQEKDKEDQPQGLVPGGAVVVLSGPHRGLYGKVEGLDPD 282
            ||||||..|||.|...|....||||.::|.|||.|||||:.|.||||||||:|||||||||||||
Mouse   203 LGLGANRMEAQDLASVGSHHPPRPDGDRENDKEGQPQGLMHGRAVVVLSGPYRGLYGKVEGLDPD 267

Human   283 NVRAMVRLAVGSRVVTVSEYYLRPVSQQEFDKNT--------LDLRQQN---GTASSRKTLWNQE 336
            |||||||||||:|:||||||.||||||||||.:|        ....|||   |||||.|...|||
Mouse   268 NVRAMVRLAVGNRIVTVSEYCLRPVSQQEFDSHTSKPGHVSQTSTEQQNRATGTASSLKAAQNQE 332

Human   337 -LYIQQDNSERKRKHLPDRQDGPAAKSEKAAPRSQHWLHRDLRVRFVDNMYKGGQYYNTKMIIED 400
             ...:|..||:||||.|||||||..|:||||||::|||||||||||:|.::|.|:||||||.|||
Mouse   333 DSKRRQKGSEKKRKHSPDRQDGPVPKTEKAAPRNKHWLHRDLRVRFIDKLHKSGRYYNTKMTIED 397

Human   401 VLSPDTCVCRTDEGRVLEGLREDMLETLVPKAEGDRVMVVLGPQTGRVGHLLSRDRARSRALVQL 465
            ||||||||||||||||||.:||||||||:||.||.||||||||..|:||.|.|||||:|.|||||
Mouse   398 VLSPDTCVCRTDEGRVLEDVREDMLETLIPKGEGHRVMVVLGPHAGKVGLLRSRDRAQSHALVQL 462

Human   466 PRENQVVELHYDAICQYMGPSDTDDD 491
            .||||||||||:||||||||.|:|:|
Mouse   463 RRENQVVELHYNAICQYMGPGDSDED 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPKOW	XP_054182812.1	G-patch_2	169..223	CDD:432700	48/53 (91%)
		KOW_GPKOW_A	259..315	CDD:240516	50/55 (91%)
		KOW_GPKOW_B	434..484	CDD:240517	39/49 (80%)
Gpkow	NP_776108.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		7/11 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	72..97		12/24 (50%)
		G-patch_2	154..211	CDD:432700	50/56 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..241		12/24 (50%)
		KOW_GPKOW_A	244..298	CDD:240516	48/53 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..367		38/71 (54%)
		KOW_GPKOW_B	431..481	CDD:240517	39/49 (80%)