| Sequence 1: | XP_016856538.1 | Gene: | ARHGEF16 / 27237 | HGNCID: | 15515 | Length: | 726 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_651960.2 | Gene: | trio / 43974 | FlyBaseID: | FBgn0024277 | Length: | 2263 | Species: | Drosophila melanogaster |
| Alignment Length: | 816 | Identity: | 158/816 - (19%) |
|---|---|---|---|
| Similarity: | 287/816 - (35%) | Gaps: | 294/816 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Human 8 AGSRTPQPPSMAQRHSDSS------LEEKLL--------------GHRFHSELRL---------- 42
Human 43 ----DAGGN---------------PASGLP---MVRGSPRVRDDAAFQP-QVPAPPQPRPPGHEE 84
Human 85 PWPIVLSTESPAALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAARRDPKLLPAPSFSL 149
Human 150 DDMDVDKDPGGMLRRN---LRNQSYRAAMKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAK 211
Human 212 NKKTLGRKRGHK--------------------------GSFKDD-------PQLYQEIQERGL-- 241
Human 242 NTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVEL--------------GIL 292
Human 293 DQLSTEE----------------------RKRQEAMFEILTSEFSYQHSLSILVEEFL------- 328
Human 329 ----QSKELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFH 389
Human 390 PYIAYCSNEVYQQRTLQKLISSNAAFREALRE-IERRPACGGLPMLSFLILPMQRVTRLPLLMDT 453
Human 454 LCLKTQGHSERYK------AASRALKAISKLVRQCNEGAHRMERMEQMYTLHTQLDFSKVKSLPL 512
Human 513 ISASRWLLKRGEL-FLVEETGLFRKIASRPTCYLFLFNDVLVVTK-KKSEESYMVQDYAQMNHIQ 575
Human 576 VEKIEPSELPLPGGGNRSSSVPHPFQVTLLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQ 640
Human 641 GLSSKGDLPQVEITKAFFAKQADEVTLQQADVVLVL 676 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ARHGEF16 | XP_016856538.1 | None | |||
| trio | NP_651960.2 | SEC14 | 13..152 | CDD:214706 | |
| SPEC | 314..>468 | CDD:238103 | |||
| SPEC | 563..778 | CDD:238103 | |||
| SPEC | 782..997 | CDD:238103 | |||
| SPEC | 897..1119 | CDD:238103 | |||
| SPEC | 1125..1226 | CDD:197544 | |||
| RhoGEF | 1287..1456 | CDD:279015 | |||
| PH1_Kalirin_Trio_like | 1462..1584 | CDD:270060 | |||
| PH | 1495..1580 | CDD:278594 | |||
| SH3_Kalirin_1 | 1643..1707 | CDD:212786 | 15/64 (23%) | ||
| RhoGEF | 1945..2122 | CDD:279015 | 42/205 (20%) | ||
| PH2_Kalirin_Trio_p63RhoGEF | 2130..2260 | CDD:270061 | 32/178 (18%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3601 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.940 | |||||