DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OXGR1 and AstC-R1

DIOPT Version :9

Sequence 1:	NP_001333123.1	Gene:	OXGR1 / 27199	HGNCID:	4531	Length:	337	Species:	Homo sapiens
Sequence 2:	NP_649040.2	Gene:	AstC-R1 / 40020	FlyBaseID:	FBgn0036790	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	88/330 - (26%)
Similarity:	142/330 - (43%)	Gaps:	41/330 - (12%)

- Green bases have known domain annotations that are detailed below.

Human    12 SDFPDYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLA 76
            :|.|.|.    :|..........:..|:||.:.::|..||.:||...:...:....:.|.:||||
  Fly    60 TDLPTYQ----HCIATRNSFADLFTVVLYGFVCIIGLFGNTLVIYVVLRFSKMQTVTNIYILNLA 120

Human    77 CTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSC 141
            ..|..:|..:|||: |.....:|.||:||||....|.....::|.:||...|..||..:.||:|.
  Fly   121 VADECFLIGIPFLL-YTMRICSWRFGEFMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISS 184

Human   142 FSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELN---TIKWYNLIL- 202
            ........|.|..|:.|..|.|.::|: .|..||          :...|.:|   .|.|.:...
  Fly   185 PRYRTLHIAKVVSAIAWSTSAVLMLPV-ILYAST----------VEQEDGINYSCNIMWPDAYKK 238

Human   203 -TATTFCL---------PLVIVTLCYTTIIHTL-THGLQTDSCLKQKAR------RLTILLLLAF 250
             :.|||.|         ||..:...|..:|..| :.|.:..:..|:|.|      ||.:.::..:
  Fly   239 HSGTTFILYTFFLGFATPLCFILSFYYLVIRKLRSVGPKPGTKSKEKRRAHRKVTRLVLTVISVY 303

Human   251 YVCFLPFHILRVIRIESRLLSISCS-IENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVC 314
            .:|:||..|.:|..|.|.......| :|..|   :::...|...|:..|.:||..:|:||:::..
  Fly   304 ILCWLPHWISQVALIHSNPAQRDLSRLEILI---FLLLGALVYSNSAVNPILYAFLSENFRKSFF 365

Human   315 STVRC 319
            ....|
  Fly   366 KAFTC 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OXGR1	NP_001333123.1	7tmA_OXGR1	34..313	CDD:320497	83/300 (28%)
		TM helix 1	34..61	CDD:320497	8/26 (31%)
		TM helix 2	68..93	CDD:320497	10/24 (42%)
		TM helix 3	106..136	CDD:320497	9/29 (31%)
		TM helix 4	148..170	CDD:320497	7/21 (33%)
		TM helix 5	195..224	CDD:320497	10/39 (26%)
		TM helix 6	234..264	CDD:320497	10/35 (29%)
		TM helix 7	281..306	CDD:320497	5/24 (21%)
AstC-R1	NP_649040.2	7tm_4	88..368	CDD:304433	80/294 (27%)
AstC-R1	NP_649040.2	7tm_1	94..353	CDD:278431	74/273 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910