| Sequence 1: | NP_055257.2 | Gene: | SIGLEC8 / 27181 | HGNCID: | 10877 | Length: | 499 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_001919202.4 | Gene: | LOC100148735 / 100148735 | -ID: | - | Length: | 440 | Species: | Danio rerio |
| Alignment Length: | 483 | Identity: | 112/483 - (23%) |
|---|---|---|---|
| Similarity: | 181/483 - (37%) | Gaps: | 143/483 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MLLLLLLLPLL---------------WGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFS 50
Human 51 YPQDGWTDSDPVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDAR 115
Human 116 KRDKGSYFFRLER--GSMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGT---LES------GH 169
Human 170 SRNLTCSVPWACKQGTPPMISWIGASVSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVT 234
Human 235 TTS-TVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRG 298
Human 299 SLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQH---ISL-------SLSLQNEGTGTS 353
Human 354 RPVSQVTLAAVGGAGATALAFLSFCIIFIIVRSCRKKSARPAAGVG-----------DTGMEDAK 407
Human 408 A--IRGSASQGPLT--------ESWKDG 425 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SIGLEC8 | NP_055257.2 | Ig | 27..151 | CDD:299845 | 27/125 (22%) |
| Carbohydrate binding. /evidence=ECO:0000269|PubMed:27357658, ECO:0007744|PDB:2N7B | 72..75 | 0/2 (0%) | |||
| Carbohydrate binding. /evidence=ECO:0000269|PubMed:27357658, ECO:0007744|PDB:2N7B | 134..138 | 0/3 (0%) | |||
| Ig | 171..229 | CDD:299845 | 13/57 (23%) | ||
| IG_like | 269..344 | CDD:214653 | 25/84 (30%) | ||
| IGc2 | 275..335 | CDD:197706 | 21/59 (36%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 410..443 | 6/24 (25%) | |||
| ITIM motif | 445..450 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 451..470 | ||||
| SLAM-like motif | 468..473 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 478..499 | ||||
| LOC100148735 | XP_001919202.4 | Ig | 27..127 | CDD:299845 | 30/143 (21%) |
| IG_like | 143..216 | CDD:214653 | 22/82 (27%) | ||
| IGc2 | 149..205 | CDD:197706 | 15/65 (23%) | ||
| IG_like | 228..301 | CDD:214653 | 25/78 (32%) | ||
| Ig_2 | 232..301 | CDD:290606 | 23/74 (31%) | ||
| IG_like | 305..387 | CDD:214653 | 18/94 (19%) | ||
| Ig_2 | 321..387 | CDD:290606 | 15/78 (19%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 56 | 1.000 | Domainoid score | I34796 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X34 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.910 | |||||