Protein Alignment TUBG2 and alphaTub84D

DIOPT Version :10

• Sequence 1: NP_001307438.1
• Gene: TUBG2 / 27175
• HGNCID: 12419
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_524264.1
• Gene: alphaTub84D / 40904
• FlyBaseID: FBgn0003885
• Length: 450
• Species: Drosophila melanogaster
• Alignment Length: 462
• Identity: 141/462 - (30%)
• Similarity: 243/462 - (52%)
• Gaps: 43/462 - (9%)

Human     3 REIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFAT--EGTDRKDVFFYQADDEHYIPRAV 65
            ||.|::.:||.|.|||...|:..|.||||.|:|.:....|  .|.|..:.||.:.....::||||
  Fly     2 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRAV 66

Human    66 LLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASG-FSQGEKIHEDIFDIIDREADGS 129
            .:||||.|:..:....|.:|::||.:...:.  .|.||:|.| ::.|::|.:.:.|.|.:.||..
  Fly    67 FVDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDLVLDRIRKLADQC 129

Human   130 DSLELQNSSRVIKGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQP 194
            ..|:         ||::.||..||||||..|.|:|||:..|.||....::|:| ..::|..||:|
  Fly   130 TGLQ---------GFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYP-APQVSTAVVEP 184

Human   195 YNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMN 259
            |||:||.....:::||..::||.|:..|....|.|:.|:::.:|:|:..|:|:.|.:||:.|.:|
  Fly   185 YNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALN 249

Human   260 NDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVST----GRDR 320
            .||.....:|:|.||:||.:..|.|:.:.:. |...:.:|.::.....:|.|.||..    |:
  Fly   250 VDLTEFQTNLVPYPRIHFPLVTYAPVISAEK-AYHEQLSVAEITNACFEPANQMVKVDPRHGK-- 311

Human   321 QTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGL 385
                 |:|...:.:|:|.|..|:.::..|:.::...|:.|.|...:|.::.:.|.:.....::.:
  Fly   312 -----YMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKV 371

Human   386 -----MMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQELIDEYH 445
                 |::|.|:|:..:.....:||.:..:.||:..:..|.|.:..|.|   :||.:
  Fly   372 QRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE---AREDL-------- 425

Human   446 AATQPDY 452
            ||.:.||
  Fly   426 AALEKDY 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBG2	NP_001307438.1	gamma_tubulin	3..444	CDD:276957	137/452 (30%)
alphaTub84D	NP_524264.1	PTZ00335	1..439	CDD:185562	141/462 (31%)