Protein Alignment TUBG2 and gammaTub23C

DIOPT Version :10

• Sequence 1: NP_001307438.1
• Gene: TUBG2 / 27175
• HGNCID: 12419
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_476804.1
• Gene: gammaTub23C / 33501
• FlyBaseID: FBgn0260639
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 463
• Identity: 353/463 - (76%)
• Similarity: 404/463 - (87%)
• Gaps: 14/463 - (3%)

Human     1 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAV 65
            ||.||||||||||||||||||||:||.||||||.|::|:||.:|.||||||||||||:|||||||
  Fly     1 MPSEIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAV 65

Human    66 LLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSD 130
            |||||||||::|:.|.|:|||||||:|||:||||||||||||:|||||:.|::||||||||||||
  Fly    66 LLDLEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASGYSQGEKLQEEVFDIIDREADGSD 130

Human   131 SLELQNSSRVIKGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPY 195
            |||         ||:||||||||||||:||:::|||.|||||||:||:||||.|||:||||||||
  Fly   131 SLE---------GFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPY 186

Human   196 NSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNN 260
            ||:|||||||..||.|||||||||||||.||||||||||||||.|||||||.||||||||.||||
  Fly   187 NSMLTLKRLTTAADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNN 251

Human   261 DLIGLIASLIPTPRLHFLMTGYTPLTTD-----QSVASVRKTTVLDVMRRLLQPKNVMVSTGRDR 320
            :||||.|.|||||:||||||||||||:|     |.:.:||||||||||||||||||:|||||.|:
  Fly   252 NLIGLTAPLIPTPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDK 316

Human   321 QTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGL 385
            ..:||||:||||||||||||||||||||||:||:|.||||||.||||||||.|||:.|.||||||
  Fly   317 SNHHCYISILNIIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGL 381

Human   386 MMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQELIDEYHAATQP 450
            |:||||||.||||.:..|:||||||.|||:|||:||:|||:.:|:|.|||.|..|:.||.|||:.
  Fly   382 MLANHTSICSLFERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLVQEYEAATRE 446

Human   451 DYISWGTQ 458
            ||:.:..:
  Fly   447 DYMQFSVK 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBG2	NP_001307438.1	gamma_tubulin	3..444	CDD:276957	344/445 (77%)
gammaTub23C	NP_476804.1	gamma_tubulin	4..440	CDD:276957	344/444 (77%)