DRSC/TRiP Functional Genomics Resources

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Protein Alignment GLA and gla

DIOPT Version :10

Sequence 1:NP_001393676.1 Gene:GLA / 2717 HGNCID:4296 Length:470 Species:Homo sapiens
Sequence 2:NP_001006103.2 Gene:gla / 450083 ZFINID:ZDB-GENE-041010-207 Length:409 Species:Danio rerio


Alignment Length:438 Identity:268/438 - (61%)
Similarity:323/438 - (73%) Gaps:42/438 - (9%)


- Green bases have known domain annotations that are detailed below.


Human    19 LALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISWSFALVAQAGVQCHDLGS 83
            :.||...:|.| |||||||.|||||||||||||||.||..:|.:||                   
Zfish     9 IGLVCLLVPAA-ALDNGLALTPTMGWLHWERFMCNTDCDADPQNCI------------------- 53

Human    84 PQPPPPRFKQFSCLILASSWNYSEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQ 148
                                  .|:|||:||::||.|||||||||::||||||.:.|||::||||
Zfish    54 ----------------------REELFMQMADVMVKEGWKDAGYEFVCIDDCWPSQQRDAQGRLQ 96

Human   149 ADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGC 213
            |||:|||.||::||:||||||||||||||||.|||||:|||.|||||||:|||||||||||||||
Zfish    97 ADPKRFPSGIKKLADYVHSKGLKLGIYADVGTKTCAGYPGSLGYYDIDAKTFADWGVDLLKFDGC 161

Human   214 YCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWK 278
            :......|.:||.:||.|||:||||||||||||||.|..|:|:|..||:.||||||:.|:.|.|.
Zfish   162 FMPDWHQLGEGYINMSSALNQTGRSIVYSCEWPLYEWQHQQPDYEAIRKTCNHWRNYGDVYDQWT 226

Human   279 SIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRH 343
            |:|||||||:..|:.:|.|||||||||||||:|||||||.:||.|||||||||||||.||||||.
Zfish   227 SVKSILDWTAEKQKIVVPVAGPGGWNDPDMLIIGNFGLSRDQQQTQMALWAIMAAPLLMSNDLRD 291

Human   344 ISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTI 408
            |.|:||.|||:|.:|||||||||||||::.:.|:||:|||||||...|||::|||||||||.:||
Zfish   292 ICPKAKELLQNKQIIAINQDPLGKQGYRILKADSFELWERPLSGNRLAVAVMNRQEIGGPRRFTI 356

Human   409 AVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLL 456
            :||.:.....|||.|.:||::|..:::|.....|.:...:|||||.||
Zfish   357 SVAIMPSWKLCNPKCNVTQIMPTYKEMGVQNLLSEVVVQVNPTGTTLL 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GLANP_001393676.1 Melibiase_2 39..363 CDD:374582 206/323 (64%)
Melibiase_2_C 366..452 CDD:407508 42/85 (49%)
glaNP_001006103.2 Melibiase_2 28..311 CDD:374582 206/323 (64%)
Melibiase_2_C 314..400 CDD:407508 42/85 (49%)

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