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Protein Alignment CHIA and Cht8

DIOPT Version :9

Sequence 1:	NP_970615.2	Gene:	CHIA / 27159	HGNCID:	17432	Length:	476	Species:	Homo sapiens
Sequence 2:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster

Alignment Length:	496	Identity:	187/496 - (37%)
Similarity:	271/496 - (54%)	Gaps:	59/496 - (11%)

- Green bases have known domain annotations that are detailed below.

Human     6 LLTGLVLIL---NLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAG-RQNNEI 66
            ||.|::|:.   :.|..|:..:.||...|:.||||||:|..::|||.|||||||||.| .:..::
  Fly    10 LLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGIEETGQL 74

Human    67 TTIEWNDVTL----------YQAFNGLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFIT 121
            ..|   |..|          .::||.||.||..||||:|:||||.|:..|:.:...|..|:.|:.
  Fly    75 RVI---DAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFVD 136

Human   122 SVIKFLRQYEFDGLDFDWEYPGSRGS-PPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVA 185
            .|::||:::.|||||.||||||.|.| ..:|:..:...::|::|..|...       .:::|||.
  Fly   137 DVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELKEGLEPFG-------FILSAAVG 194

Human   186 AGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTD----TGSNAYLNVDYV 246
            :...:.:..|:||.:..|||.|:||.|||||.|:...|.|:|||....|    :|....||||.|
  Fly   195 SAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAV 259

Human   247 MNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLK 311
            :.||...||||||||:|.|.||.:|.|:.......|||..|.|.||.|::|.|:..|.|:|..::
  Fly   260 VKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMME 324

Human   312 NGA-TQGWDAPQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQG 375
            ... ||.|:|.|:|||||:...||||::.:|..:|||::..|..||.|:|:::.|||.|| |.|.
  Fly   325 REEWTQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGT-CGQQ 388

Human   376 KFPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSG-SSSSGGSSGGSGF-CAVRANGLY 438
            .:||:..:.:.|                     .|....|| ::.|...|...|| |...|...|
  Fly   389 PYPLLHEINRVL---------------------FGGNTPSGLTTESNRESPSEGFSCPADAPAGY 432

Human   439 ---PVANNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA 476
               |  :|.:.|::|..|.|:..:|.:||.||.....||::
  Fly   433 IRDP--DNCSKFYYCSGGKTHNFDCPSGLNFDLDTKSCNYS 471

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.