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Protein Alignment CHIA and Idgf3

DIOPT Version :9

Sequence 1:	NP_970615.2	Gene:	CHIA / 27159	HGNCID:	17432	Length:	476	Species:	Homo sapiens
Sequence 2:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	117/453 - (25%)
Similarity:	198/453 - (43%)	Gaps:	88/453 - (19%)

- Green bases have known domain annotations that are detailed below.

Human     4 LILLTGLVLILNLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCL--CTHLIYAFAG--RQNN 64
            |.|...|.::...::.:|..|.|::.:....|.||.:|...:|:..|  ||||:|.:||  ..|.
  Fly     7 LSLALSLAVLAQFKVSAAPNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVNADNY 71

Human    65 EITTIEWNDVTLYQ----AFNGLKNKNSQLKTLLAIGG---WNFGTAPFTAMVSTPENRQTFITS 122
            |:.:|. ..:.|.|    ....:|.:...:|.||::||   ...|......:.|..:..:.||.|
  Fly    72 EMQSIN-KRLDLEQRHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESGQQGHRRFIES 135

Human   123 VIKFLRQYEFDGLDFDWEYP--------GSRGSPPQD-KHLF-----------------TVLVQE 161
            ....:|:|.|||||...:.|        |..||..:. |..|                 |.|:::
  Fly   136 ARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVTALIKD 200

Human   162 MREAFEQEAKQINKPRLMVTAAVAAGISNIQSG--YEIPQLSQYLDYIHVMTYDLHGSWEGYTGE 224
            :..|.:|.       .|:::..|   :.|:.|.  |:.|.::..||:|::.|:|.      .|.:
  Fly   201 LSAALKQN-------DLLLSLTV---LPNVNSSWYYDAPSIAPSLDFINLGTFDF------LTPQ 249

Human   225 NSPL---YKYPT--DTGSN--AYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIG 282
            .:|.   :..||  ..|.|  .:.|:::.|.:|.....||.|:.:|..|||.::.:|..|... |
  Fly   250 RNPEEADFSAPTYEAVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDS-G 313

Human   283 AP----TSGAGPAGPYAKESGIWAYYEICTFL---KNGATQGWDAP---------QEVPYAYQG- 330
            .|    |.|..||||.:|:.|:..:.|||:.:   .|...:|.:||         :...||::.
  Fly   314 MPVVPSTQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRAA 378

Human   331 ------NVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKAL 387
                  .:|:.||:..|...||.:.:....||..::.:..|||.|. |...:||::..:|..|
  Fly   379 DENGDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQ-CTNDRFPMLRAIKYRL 440

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.